沙门氏菌耐药机制的研究进展  

The Resistance Mechanisms of Salmonella Progress

作　　者：胡彩光[1] 高维凡[1] 教郁[1] 

机构地区：[1]沈阳农业大学,辽宁沈阳110866

出　　处：《现代畜牧兽医》2013年第4期53-56,共4页Modern Journal of Animal Husbandry and Veterinary Medicine

摘　　要：沙门氏菌是肠杆菌科中一种重要的人畜共患病原菌,是细菌性食物中毒的重要致病菌。沙门氏菌的多重耐药问题一直是医学、兽医学、公共卫生学关注的焦点。目前沙门氏菌耐药机制主要集中在靶位基因突变、药物外排、可移动基因元件及其转移、钝化酶和灭活酶引起的耐药性等方面,本文就以上几个方面对沙门氏菌的耐药机制作一综述。Salmonella is an important zoonotic pathogen of Enterobacteriaceae, an important pathogen of bacterial food poisoning. The multi-drug resistant of salmonella has been the focus of medicine, veterinary science and public health. Drug resistance mechanisms of salmonella are mainly concentrated in the target gene mutations, drug efflux, movable genetic elements and their transfer, the passivation enzyme and the inactivated enzyme, etc. This review focuses on research progress related to elucidating mechanism of antibiotic resistance in salmonella.

关 键 词：沙门氏菌 耐药机制 

分 类 号：S852.61[农业科学—基础兽医学]