留置PICC导管对非血液系统恶性肿瘤化疗患者血液流变学影响及其临床意义  

The impact of PICC on the blood rheology of nonhematologic malignancy patients

作　　者：陈谊月[1] 夏春芳[1] 彭永芝[1] 杨群[1] 王文丽[1] 赵丽萍[1] 

机构地区：[1]中南大学湘雅二医院护理部,湖南长沙410011

出　　处：《中国现代医学杂志》2013年第6期102-105,共4页China Journal of Modern Medicine

基　　金：湖南省科技厅资助(No:2010SK3107)

摘　　要：目的比较非血液系统恶性肿瘤患者化疗前后血液流变学的变化趋势,并探讨留置PICC导管对非血液系统肿瘤化疗患者血液流变学的影响。方法分别测定37例留置PICC导管(试验组)及36例未留置PICC导管(对照组)非血液系统恶性肿瘤患者化疗前后血液流变学指标,观察化疗后的血液流变学变化趋势,并对两组患者的血液流变学指标进行比较分析。结果对照组化疗后全血黏度值(切变率1、5、50、100、200s-1)、全血低切相对指数、全血高切相对指数、全血低切还原黏度、全血高切还原黏度、红细胞刚性指数均低于化疗前(P<0.05);试验组化疗后所有血液流变学指标与化疗前比较,差异均不具有显著性(P>0.05);试验组化疗后所有血液流变学指标与对照组化疗后比较,差异均不具有显著性(P>0.05)。结论留置PICC导管对非血液系统恶性肿瘤化疗患者血液流变学没有影响。【Objective】To study the trends in blood rheology in patients with malignant tumor after chemotherapy and to explore the effect of PICC on hemorheology in patients with non-hematologic malignancies chemotherapy.【Methods】Were measured in 37 cases PICC（the experimental group） and 36 cases did not undergo（the control group） hemorheological changes in patients with non-hematologic malignancies before and after chemotherapy,observation the non-hematologic malignancies patients after chemotherapy changes in the hemarheology trends,and the situation of the hemorheology changes in patients with non-hematologic malignancies were compared between the two groups.【Results】The control group after chemotherapy,great majority hemorheological indicators were lower than those before chemotherapy（P 0.05）;there were no hemorheological indicators differences between before and after chemotherapy in the group of row PICC（P 0.05）;there were no hemorheological indicators differences between the two groups of patients after chemotherapy（P 0.05）.【Conclusion】Rowed PICC on blood rheology have no effect in chemotherapy patients with non-hematologic malignancies.

关 键 词：非血液系统恶性肿瘤 化疗 血液流变学 PICC 

分 类 号：R730[医药卫生—肿瘤]