Adenoid cystic carcinoma in the maxillary gingiva: a case report and immunohistochemical study  

作　　者：Chi Zhao Jin-Zhong Liu Shu-Bin Wang Shi-Chang Wang 

机构地区：[1]Zhengzhou University School and Hospital of Stomatology [2]Department of Pathology,The Fourth Affiliated Hospital of Zhengzhou University [3]Department of Oral and Maxillofacial Surgery, The Fourth Affiliated Hospital of Zhengzhou University

出　　处：《Cancer Biology & Medicine》2013年第1期52-54,共3页癌症生物学与医学（英文版）

摘　　要：Gingival adenoid cystic carcinoma (ACC) is a rare malignancy. We describe the diagnosis and treatment of a 43 year- old woman who presented with a persistent oral ulcer for approximately 1 year, and subsequent pain in the left posterior maxillary region. Clinical examination revealed an ulcer in the left upper molar gingiva, with swelling in the region from the second premolar to the third molar. X-ray images demonstrated the involvement of the maxillary alveolar bone. The histopathological and immunohistochemical features were diagnostic of ACC. ACC is often presented as a gingival lesion; thus, it may easily be neglected by patients. The identification of this tumor using specific pathological analyses prevents misdiagnosis and enables clinicians to determine the appropriate treatment. In this case, no recurrence or distant metastasis was observed after 2 years of follow-up.Gingival adenoid cystic carcinoma （ACC） is a rare malignancy： We describe the diagnosis and treatment of a 43 yearold woman who presented with a persistent oral ulcer for approximately 1 year, and subsequent pain in the left posterior maxillary region. Clinical examination revealed an ulcer in the left upper molar gingiva, with swelling in the region from the second premolar to the third molar. X-ray images demonstrated the involvement of the maxillary alveolar bone. The histopathological and immunohistochemical features were diagnostic of ACC. ACC is often presented as a gingival lesion; thus, it may easily be neglected by patients. The identification of this tumor using specific pathological analyses prevents misdiagnosis and enables clinicians to determine the appropriate treatment. In this case, no recurrence or distant metastasis was observed after 2 years of follow-up.

关 键 词：GINGIVAL MAXILLA adenoid cystic carcinoma IMMUNOHISTOCHEMISTRY 

分 类 号：R739.8[医药卫生—肿瘤]