下咽癌肉瘤临床病理特征的研究  

Clinicopathological characteristics of hypopharyngeal carcinosarcoma

作　　者：郭永伟[1] 严文洪[1] 赵霞[1] 高海河[1] 周仲文[2] 

机构地区：[1]复旦大学附属华山医院耳鼻咽喉-头颈外科,上海200040 [2]复旦大学附属华山医院病理科

出　　处：《临床耳鼻咽喉头颈外科杂志》2013年第9期484-486,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨下咽癌肉瘤的临床病理学特征、诊断和鉴别诊断。方法:报道1例经病理证实的下咽癌肉瘤患者的临床资料,结合文献复习进行分析。结果:患者通过手术切除病变,病理检查证实为鳞状细胞癌横纹肌肉瘤,术后行放化疗,恢复良好,随访18个月无复发。结论:下咽癌肉瘤是一种极为罕见的恶性肿瘤,具有特征性的组织病理学、免疫组织化学及临床特点,需与肉瘤样癌、喉癌的放疗反应等相鉴别。下咽癌肉瘤的治疗应首选手术切除。对局部晚期、术后残留、肉眼切除范围欠安全的头颈部癌肉瘤患者应行放疗并及时随访。Objective：To study the clinicopathological characteristics, diagnosis and differential diagnosis of hypopharyngeal carcinosarcoma. Method：Clinical data of one case with hypopharyngeal carcinosarcoma proved by pathology were analyzed retrospectively. The related literatures were reviewed. Result：The masses were surgically removed,and the postoperative diagnosis was confirmed to be carcinosarcoma by histopathological examination. After radiotherapy and chemotherapy, the patient recovered well postoperatively without recurrence during 18- month follow-up . Conclusion：Carsinosareoma of the hypophal：ynx is an extremely rare malignant tumor with dis- tinctive histological, clinical and immunohistochemical features. The final diagnosis depends on histopathology. This tumor should be differentiated from other tumors such as sarcomatoid carcinoma and the reaction of radiother- apy of carcinoma. Surgery is the proper treatment strategy for carsinosarcoma of the hypopharynx. The patients with locally advanced, postoperative residualtumor or tumor without clear safe surgical margin should undergo ra- diotherapy, and the postoperative follow up should be in time.

关 键 词：癌肉瘤 下咽 诊断 治疗 

分 类 号：R739.6[医药卫生—肿瘤]