食管癌术后谵妄症的发病率及其原因  

Incidence and causes of postoperative delirium in patients with esophageal cancer

作　　者：续国武[1] 郑锴[1] 张鹏[1] 

机构地区：[1]天津医科大学总医院心胸外科,天津市300052

出　　处：《世界华人消化杂志》2013年第11期1014-1019,共6页World Chinese Journal of Digestology

摘　　要：目的:调查食管癌术后谵妄的发病率并对其发病原因进行进一步探析.方法:回顾性地分析了2010-01/2012-12在天津医科大学总医院心胸外科行食管切除术的124例食管癌患者临床资料,并采用SPSS17.0软件进行t检验、2检验,对结果进行统计学分析.结果:124例患者中有60例(48.4%)发生了术后谵妄.结果表明高龄(P=0.007)、既往相关精神疾病史(P=0.0001)、术后长时间机械通气(P=0.0001)、术后延长ICU住院时间(P=0.0001)、术后延长经口禁食水时间(P=0.0001)以及术后并发症的发生(P=0.002)均与术后谵妄明显相关.结论:食管癌患者术后谵妄是一个不容忽视的问题.术后谵妄的发生与高龄、既往相关精神疾病史、术后长时间机械通气、术后延长ICU住院时间、术后延长禁食水时间以及术后并发症相关.AIM： To investigate the incidence and causes of postoperative delirium in patients with esophageal cancer. METHODS： We conducted a retrospective cohort analysis of 124 patients who had undergone an esophagectomy at Tianjin Medical University General Hospital from January 2010 to December 2012. All quantitative data and all qualitative data were analyzed using Student’s t test and Chi-square test, respectively. RESULTS： Postoperative delirium developed in 60 （48.4%） of 124 patients. Elder age （P = 0.007）, history of mental illness （P = 0.0001）, longer period of time under mechanical ventilation after surgery （P = 0.0001）, longer ICU stay after surgery （P = 0.0001）, longer period of prohibiting drinking and eating from mouth after surgery （P = 0.0001）, and occurrence of postoperative complications （P = 0.002） were significantly associated with the development of postoperative delirium. CONCLUSION： The development of postoperative delirium in patients with esophageal cancer is a problem that should not be ignored. Causes of postoperative delirium include elder age, history of mental illness, longer periods of time under mechanical ventilation after surgery, longer postoperative ICU stays, longer periods of prohibiting drinking and eating from mouth after surgery, and occurrence of postoperative complications.

关 键 词：食管癌 术后谵妄 发病率 原因 

分 类 号：R735.1[医药卫生—肿瘤]