急性缺血性脑卒中患者肾功能状况及其相关因素的研究  

Prevalence of kidney dysfunction and related factors in patients with acute ischemic stroke

作　　者：陈丹[1] 左红霞[2] 黄建新[1] 史科其[1] 黄立华[2] 

机构地区：[1]浙江省慈溪市人民医院肾内科,浙江慈溪315300 [2]浙江省慈溪市人民医院神经内科,浙江慈溪315300

出　　处：《中国现代医生》2013年第12期36-38,共3页China Modern Doctor

基　　金：浙江省慈溪市科技计划项目(CN2009021)

摘　　要：目的探讨急性缺血性脑卒中住院患者肾功能状况及肾功能下降患者的临床特征。方法选择2009年6～11月慈溪市人民医院神经内科住院的87例缺血性脑卒中患者,以MDRD公式计算肾小球滤过率,将eGFR<90 mL/(min.1.73 m2)定义为GFR下降,分析GFR下降患者的临床特征。结果 87例患者中GFR下降者有47例(54.02%),其中eGFR<60 mL/(min.1.73 m2)6例(6.90%)。GFR下降组患者发病年龄、高血压患病率、颈动脉内膜中层厚度、硬化斑块指数均显著高于GFR正常组(P<0.05)。回归分析显示,年龄、高血压病史是急性缺血性脑卒中患者GFR下降的独立影响因素。结论急性缺血性脑卒中患者伴GFR下降的比例较高,GFR下降组患者合并的血管危险因素更多。Objective To investigate the prevalence of kidney dysfunction in patients with acute ischemic stroke and its related factors. Methods A total of 87 hospitalized patients with acute ischemic stroke from Jun 2009 to Nov 2009 were recruited. GFR was calculated according to MDRD equation, kidney dysfunction was defined as 〈 90 mL/（min·1.73 m2）. The clinical characters of patients were analyzed. Results 47 patients （54.02%） had decreased eGFR and 6 patients （6.9%） had moderately decreased eGFR（〈 60 mL/（min. 1.73 m2）. Age, prevalence of hypertension, carotid artery intima-media thickness and the plaque index in patients with kidney dysfunction were significantly higher （P 〈 0.05）. Logistic regression revealed that age and hypertension were risk factors of kidney dysfunction. Conclusion The prevalence of kidney dysfunction is high in acute ischemic stroke patients, and they have more risk factors.

关 键 词：肾功能减退 急性缺血性脑卒中 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]