功能性消化不良患者的胃液体排空和胃感觉阈异常  

Abnormality of Gastric Liquid Emptying and Sensory Threshold in Patients with Functional Dyspepsia

作　　者：侯晓华[1] 李启祥[1] 谢小平[1] 刘永革[1] 朱良如 

机构地区：[1]武汉同济医科大学附属协和医院消化内科,430022

出　　处：《胃肠病学》2000年第3期166-168,共3页Chinese Journal of Gastroenterology

摘　　要：目的：检测功能性消化不良（FD）患者的胃液体排空和胃感觉阈，以了解两者之间的联系。方法：采用超声法测定68例FD患者和29例正常对照者饮水500ml后的胃体-底前后径变化，以了解胃液体排空情况；同时记录受检者摄入温水后出现上腹不适感觉时的饮水量以表示胃最小感觉容量（感觉阈）。结果：FD患者的胃液体半排空时间较正常人明显延迟（FD患者：31.06min±10.29min，正常人：24.63min±4.86min，P＜0.001），胃感觉阈显著下降（FD患者：412.50ml±94．47ml，正常人：478.33ml±35.78ml，P＜0．001），50％（34／68）的患者胃感觉过敏。胃感觉阈与胃液体半排空时间的相关分析表明，胃感觉阈越低，排空延迟越明显（P＜0.05）。结论：FD患者不但存在胃排空延迟，还存在胃感觉过敏，两者有一定的相关性。Background/Aims: To study the relationship between gastric liquid emptying and gastric sensory threshold in patients with functional dyspepsia (FD). Methods: Gastric liquid emptying was measured by ultrasonography in 68 FD patients and 29 healthy controls after drinking 500 ml water. Upper abdominal discomfort and the volume of water drinking at the same time were recorded. This volume was regarded as the minimal sensory threshold. Results: The average time of 50% gastric liquid emptying in patients with FD (31.06 min ± 10.29 min) was longer than that in healthy controls (24.63 min ±4.86 min, P<0 .001), the sensory threshold of stomach was also lower (412.50 ml±94.47 ml) than that in volunteers (478.33 ml± 35.78 ml, P< 0.001). 50% FD patients (34/68) had gastric hypersensitivity. The relevance analysis of gastric sensory threshold and the time of 50% gastric liquid emptying showed that the lower the sensory threshold in patients, the longer the delay of gastric emptying. Conclusions: The patients with FD have not only delayed gastric liquid emptying, but also gastric hypersen sitivity, which is related to delay of gastric liquid emptying.

关 键 词：消化不良 胃排空 感觉阈 

分 类 号：R573[医药卫生—消化系统]