食管癌贲门癌术后早期肠内营养的安全性和临床疗效  

The safety and clinical efficacy studies of esophagus and cardia postoperative early enteral nutrition

作　　者：黄向华[1] 王伟[1] 王强[1] 陈赛华[1] 樊怿辉[1] 施民新[1] 

机构地区：[1]南通大学附属肿瘤医院,南通226361

出　　处：《中国肿瘤临床与康复》2013年第4期389-391,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探析食管癌贲门癌患者术后行早期肠内营养的疗效和安全性。方法选择2008年10月至2012年5月间收治的80例行根治手术治疗的食管、贲门癌患者,将患者随机分为行早期肠内营养的EN组(enteral nutrition,40例)和行早期肠外营养的PN组(parenteral nutrition,40例),两组患者均在术后进行营养支持治疗或者静脉营养,观察和测定以及分析比较患者手术第1、8天相关营养指标,同时分析患者在术后恢复期间并发症发生情况、肠道功能恢复时间、营养支持治疗相关费用以及住院时间等临床指标。结果两组患者在经过营养支持治疗后,术后第8天相比于第1天血清总蛋白、前白蛋白、白蛋白和淋巴细胞计数等相关指标均有所升高,EN组患者相比于PN组患者有明显升高(P<0.05);PN组患者术后并发症发生率明显高于EN组患者(P<0.05),两组患者在肠道功能恢复时间、营养支持治疗费用和住院时间等方面比较,EN组患者明显优于PN组患者,差异有统计学意义(P<0.05)。结论临床上早期对食管、贲门癌患者行根治术后进行肠内营养支持治疗具有较好的安全性,且疗效显著,同时患者所需承担的医疗费用相对较少,与肠外营养比较具有更大优势。Objective To explorate the clinical efficacy and security of esophagus and cardia canc- er patients in the postoperative early enteral nutrition. Methods Our hospital from October 2008 to May 2012, 80 cases were treated by radical surgical treatment of esophageal and gastric cardia patients for the study, the patients were randomly divided into two groups, each group of 40 patients, early enteral EN group nutrition in patients with early parenteral nutrition in patients with PN group, patients in both groups in postoperative nutrition support therapy or intravenous nutrition, observation and determination, as well as analysis and comparison of patients surgery day 1,8 nutrition indicators, while analysis patients complica- tions occurred during the postoperative recovery situation, the time to recovery of bowel function, nutritional support treatment costs and hospital stay associated clinical indicators for statistical analysis. Results The two groups of patients after treatment of nutritional support in eight days after treatment and compared to the first day of serum total protein, prealbumin, albumin, lymphocyte count and biochemical indicators were el- evated, and pre-treatment compare declined, two sets of indicators compare EN patients compared to pa- tients in the PN group （ P 〈 0. 05 ）, significantly higher （ P 〈 0. 05 ） ; PN patients in the postoperative recov- ery complications before treatment the incidence was significantly higher than the EN group （ P 〈 0. 05 ） in patients to compare the two groups of patients in the recovery of bowel function, time and cost spent in nutri- tion therapy, hospitalization time, and the EN group were significantly better than patients of PN group （P 〈 O. 05 ）. Conclusions The clinical early esophageal and gastric cardia patients after radical enteral nutrition support therapy with better security, and the effect is significant, while medical costs borne by pa- tients is relatively small, and parenteral nutrition the comparative analysis, has a g

关 键 词：食管癌 贲门癌 肠内营养 临床效果 

分 类 号：R735.1[医药卫生—肿瘤] R735.2[医药卫生—临床医学]