抗生素高产炭样小单孢菌的热诱变育种  

Screening of Prolific Micromonospora carbonacea in Antibiotics Production by Heat Mutagenesis

作　　者：李瑾[1] 黄运红[1] 李鹿鸣[1] 彭伟梦[1] 龙中儿[1] 

机构地区：[1]江西师范大学生命科学学院,南昌330022

出　　处：《生物技术通报》2013年第4期147-151,共5页Biotechnology Bulletin

基　　金：江西省科技支撑计划项目(201 12BBF60026);公益性行业(农业)科研专项(201203072)

摘　　要：采用热诱变处理,结合庆大霉素抗性筛选法筛选,对产抗生素的炭样小单孢菌JXNU-1进行选育,最终获得抗生素高产菌株JXNU-1-16-R4。结果显示,其抗生素产率比出发菌株提高了98.53%。Heating mutagenesis effect, combined with gentamicin resistance screening, was used in breeding of prolific Micromonospora carbonacea in antibiotics production from the strain of Micromonospora carbonacea JXNU-1. The overproducing strain JXNU-1-16-R4 was screened with the production of antibiotics is 98.53% more than that of the original strain.

关 键 词：炭样小单孢菌 热诱变 抗性筛选 

分 类 号：TQ927[轻工技术与工程—发酵工程]