氧化应激与帕金森病及补肾中药的研究进展  

Progress in Study of Oxidative Stress and Kidney-Tonifying Chinese Herbs in Parkinson's Disease

作　　者：许艺惠[1] 黄露芬[2] 蔡晶[1] 

机构地区：[1]福建中医药大学福建中西医结合研究院,福建福州350122 [2]福建中医药大学中西医结合学院,福建福州350122

出　　处：《中华中医药学刊》2013年第5期1128-1130,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：福建省自然基金杰青项目(2009J06018);陈可冀中西医结合发展基金资助项目(CKJ2010025)

摘　　要：帕金森病是老年人最常见的运动障碍疾病,主要病变在黑质,研究表明黑质多巴胺能神经元变性缺失与氧化应激、细胞凋亡等多种机制有关。近年来,补肾中药在帕金森病的临床治疗方面取得一定的进展。现就氧化应激与帕金森病及补肾中药的作用等方面的研究进展作一综述。Parkinson＇s disease（PD） is a movement disorder and most common in elderly people,and the main pathological changes are in the substantia nigra.The studies have indicated that degeneration and lost of dopaminergic neurons of the substantia nigra are associated with many mechanisms,such as oxidative stress,cell apoptosis.In recent years,the kidney-tonifying Chinese herbs have made certain progress in the clinical treatment of Parkinson＇s disease.In this review,the role of oxidative stress and the kidney-tonifying Chinese herbs in PD is summarized briefly.

关 键 词：氧化应激 帕金森病 补肾中药 

分 类 号：R741[医药卫生—神经病学与精神病学]