667例甲状腺癌的临床病理分析及治疗  

Analysis of the clinicopathological features and therapy of 667 cases of thyroid cancer

作　　者：姚瑶[1] 张园[1] 夏雷[1] 

机构地区：[1]江苏省肿瘤医院头颈外科,江苏南京210009

出　　处：《中国肿瘤外科杂志》2013年第2期76-78,共3页Chinese Journal of Surgical Oncology

摘　　要：目的探讨甲状腺癌患者的临床病理特征及治疗策略。方法回顾性分析2006年1月至2012年4月江苏省肿瘤医院收治的667例甲状腺癌患者临床病理资料。结果 40～59岁为甲状腺癌高发年龄段,女性发病率明显高于男性,乳头状癌为主要病理类型。中央区淋巴结转移率为48%,侧颈淋巴结转移率为38%,中央区淋巴结无转移而侧颈淋巴结转移者占5%,单侧肿瘤双颈淋巴结转移率为6%。存在甲状腺腺外侵犯的病例中,中央区淋巴结有转移占75%,中央区及侧颈淋巴结同时存在转移占59%。在髓样癌病例中55%出现中央区及侧颈淋巴结转移。微小癌常合并淋巴细胞甲状腺炎、腺瘤性甲状腺肿和结节性甲状腺肿。结论对甲状腺癌临床病理特征的分析能提高对甲状腺癌的认识,有助于对甲状腺癌规范化诊断和治疗提供参考。Objective To analyze the clinicopathological features and treatment of thyroid cancer. Methods The clinical data of 667 patients with thyroid cancer from January 2006 to April 2012 were retrospectively analyzed. Results Thyroid cancer occurred in the patients aged from 40 to 59 years old. The incidence of female was significantly higher than that of male. Papillary carcinoma was the major pathological types. In this series of patients, the metastasis rates of central lymph node and lateral cervical lymph node were 48% and 38%. The metastasis rate of lateral cervical lymph node with negative central lymph node was 5%. The metastasis rate of bilateral lymph node in unilateral tumor was 6%. In patients with extrathyroidal extension, the metastasis rate of central lymph node was 75% and the metastasis rate of coexistence of central and lateral cervical lymph node was 59%. In patients with medullary carcinoma, the metastasis rate of concurrence of central and lateral cervical lymph nodes was 55%. Microcareinoma was often accompanied by lymphocytic thyroiditis, adenomatous goiter and nodular goiter. Conclusions Analysis of elinicopathological features of thyroid cancer can improve the understanding of its nature history and help to standardize the diagnosis and treatment of thyroid cancer.

关 键 词：甲状腺癌 临床病理特征 治疗 

分 类 号：R736.1[医药卫生—肿瘤]