代谢组学在中医证候实质研究中的运用  

Application of Metabonomics in Research essence of TCM Syndrome

作　　者：冯桂贞[1] 秦丹[2] 吕崇山[2] 

机构地区：[1]厦门市中医院脑科,福建厦门361009 [2]厦门大学医学院中医系,福建厦门361005

出　　处：《亚太传统医药》2013年第5期56-57,共2页Asia-Pacific Traditional Medicine

摘　　要：代谢组学是继基因组学、转录组学和蛋白组学之后新近发展起来的一种组学方法。代谢组学通过对体液中小分子代谢产物的检测反映人体的生理或病理状态,而中医的"证"是对疾病过程中某一阶段病因、病位、病性及病势等的病理概括。显而易见,代谢组学的出现,为中医证候实质的研究带来新的思路。Metabonomics is a new developing omics after genomics, transcriptomics and proteomics. It can detect small molecular metabolite profiling in the human body fluid to reflect human physiological and pathological state, and TCM syndrome is a pathologic generalization in a stage in the progress of the disease of cause, location, nature and trend of disease. Obviously, it brings a new idea for using metabonomics to study the essence of TCM syndrome.

关 键 词：代谢组学 中医证候 整体观念 

分 类 号：R22[医药卫生—中医基础理论]