帕病1号方治疗强直少动型早期帕金森病28例临床观察  

Clinical Study of PabingⅠFormula for 28 Early Stage Parkinson of Stiffness and Less Dynamic Pattern

作　　者：赵彩燕[1] 雒晓东[2] 林明欣[1] 

机构地区：[1]广州中医药大学,广州510405 [2]广东省中医院,广州510000

出　　处：《世界中医药》2013年第4期395-396,共2页World Chinese Medicine

基　　金：广东省科技计划项目(编号:2011971)

摘　　要：目的:观察帕病1号方对强直少动型早期帕金森病的临床疗效。方法:将58例早期帕金森病患者随机分为2组,治疗组28例予帕病1号方治疗,对照组30例予美多芭治疗,疗程均为2个月。结果:帕病1号方和美多芭均可改善早期帕金森患者的运动症状(P<0.01),且疗效相仿(P>0.05);帕病1号方和美多芭均可改善早期帕金森病患者生活质量(P<0.01),但帕病1号方疗效优于美多芭(P<0.05)。结论:帕病1号方治疗强直少动型早期帕金森病在改善运动症状上疗效与美多芭相仿,在改善生活质量上则优于美多芭。Objective：To observe the effect of Pabing I Formula for early stage Parkinson of stiffness and less dynamic pattern. Meth- ods：Fifty-eight early stage Parkinson patients were randomed into two groups, the treatment group （ N = 28 ） received Pabing I Formula, the control group （ N = 30） received madopar. The treatment last for 2 months. Results： Both groups showed improved motor function compared with before treatment （ P 〈 0. O1 ）, with similar efficacy （ P 〉 O. 05 ） ; patient of both groups had improved quality of life com- pared with before treatment （P 〈0. 01 ） , and Pabing I Formula group showed better efficacy （P 〈0. 05）. Conclusion：Pabing I Formula showed motor function improvement similar to the effect of madopar, and was superior to madopar group in improving the quality of life of the patients.

关 键 词：帕金森病 中医药疗法 帕病1号方 强直少动型 

分 类 号：R742.5[医药卫生—神经病学与精神病学]