脂氧素A4与炎症性疾病  

Lipoxin A4 and inflammatory diseases

作　　者：王学莹[1] 关为群[1] 

机构地区：[1]福建医科大学附属协和医院口腔科,福州350001

出　　处：《国际口腔医学杂志》2013年第3期334-338,共5页International Journal of Stomatology

摘　　要：脂氧素A4为花生四烯酸代谢产物,具有抗炎和促进炎症消退的作用。本文就脂氧素的合成和作用及代谢、脂氧素替代物、脂氧素A4与炎症等研究进展作一综述,探讨其应用于口腔黏膜病研究的可能性。Lipoxin A4 （LXA4） is one of the products of arachidonic acid metabolic pathway. It displays promising bioaction of anti-inflammatory, as well as pro-resolving. In this review, the author focus on the synthesis, function, and metabolism of lipoxin and the research development of LXA4 and its analogs, LXA4 and inflammatory, then to explore the possibilities of its application in oral mucosal disease research.

关 键 词：脂氧素 炎症 消退 

分 类 号：R363[医药卫生—病理学]