部分脾栓塞治疗肝硬化门脉高压及脾亢  

Partial splenic embolization treatment on portal hypertension and hypersplenia caused by cirrhosis

作　　者：王培珍[1] 孔宪牛[1] 刘锦堂[1] 徐岩 薛桂芹[1] 

机构地区：[1]山东省临沂市人民医院,276003 [2]临沂市肿瘤医院

出　　处：《胃肠病学和肝病学杂志》2000年第3期227-228,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的进一步观察部分脾栓塞治疗肝硬化门静脉高压及脾功能亢进（简称脾亢）的应用价值。方法经下腔动脉插管对部分牌动脉用明胶海绵颗粒进行栓塞，观察其治疗作用。结果本文２２例术后外周血白细胞和血小板计数均回升，其中１９例恢复至正常水平，３例部分缓解，门静脉及脾静脉回缩，食道静脉曲张程度改善，凝血酶原时间（ＰＦ）缩短，凝血酶原活动度（ＰＦＡ）增加，脑病发作次数减少，血氨水平下降，未出现严重并发症。结论部分脾栓塞是治疗肝硬化牌功能亢进、门静脉高压、缓解肝性脑病安全有效的治疗方法。Aim To observe more deeply the clinical value of Partial splenic embolization (PSE) in beating patients with portal hypertension and hyperlenia caused by Cirrhosis.Method Partial splenic artery was embolized with particulate gelatin sponge by tube inserted throuqh inferior vana cave. The efficacy of treatment was observed. Result Peripheral blood leukocyte and platelet count in all the patients in this article increased, 19 cases restored to normal , and 3 cases partially recovered. The diameter of splenic vein and portal vein narrowed back. The degree of esophageal varices decreased, prothrombin time shortened, prothrombin actvity. increased, the frequency that hepatic encephalopaty attack decreased. The level of blood ammonia is lower and no severe complication happened after the operation Conclusion PSE is a safe and effective treatment in treating portal hypertension and hypersplenism caused by cirrhosis, and in alleviating hepatic encephalopathy.

关 键 词：肝硬化 脾功能亢进 脾栓塞 治疗 

分 类 号：R575.205[医药卫生—消化系统]