肝非唾液酸糖蛋白受体显像与肝储备功能关系的研究  

The Clinical Study of the Relations Between ASGP-R Developing and the Hepatic Reserve Function

作　　者：任辉[1] 朱岩嘉[1] 于波[1] 尹艳华 罗夫[3] 冯军 

机构地区：[1]教学医院.齐齐哈尔市第一医院 [2]齐齐哈尔市铁锋区医院 [3]沈阳市解放军第202医院,161000

出　　处：《齐齐哈尔医学院学报》2000年第4期366-367,共2页Journal of Qiqihar Medical University

摘　　要：目的　探讨肝非唾液酸糖蛋白受体显像与肝储备功能关系。方法　对 19例肝硬变、门脉高压患者用99mTc标记NGA(新半乳糖白蛋白 )与ASGP -R(肝非唾液酸糖蛋白受体 )结合法 ,观测肝受体显像 ;用超声多普勒观测肝血流的变化。结果　肝硬变组的MRI、HBF与ABCHE均呈正相关 ,与总胆红素呈显著负相关。行肝切除贲门周围血管离断术 7例 ,术后 1周重新评估肝功能分级 :术前肝功能Ⅰ级 2例无变化 ;术前肝功能Ⅱ级 5例 ,术后 2例出现大量腹水 ,肝功能降为Ⅲ级。Objective To investigate the relation between ASGP-R developing and the reserve function of hepar.Methods By the way of NGA and ASGP-R marked with 99m Tc in 19 cases of hepatocirrhosis and portal hypertension,than the variation of HBF was shown by ultrosound doppler.Results The MRI and HBF has positive correlation with ABchE,and has negative correlation with TBIL.Ligtion of pericardial blood vessel was done in 7 cases,then Liver function was reassessed one postoperative week.Two case did not vary,the function of hepar remained grade one.But two cases occured gread ascites,and hepatic function descended grade three from grade two.Conclusion From statistics and clinical observation,the way to determine HBF can be used to estimate the hepatic reserve function.

关 键 词：肝非唾液酸糖蛋白受体 肝血流量新半乳糖白蛋白 

分 类 号：R575[医药卫生—消化系统]