剥夺睡眠脑电图对儿童精神运动性癫痫的诊断价值及其影响因素  

Diagnostic value and its influence factors of sleep-deprived electroencephalogram on pediatric psychomotor epilepsy

作　　者：陈连红[1] 陆燕芬[1] 王超[2] 施佳奇[2] 庞清忠[2] 

机构地区：[1]上海交通大学附属儿童医院(上海市儿童医院)神经内科,200040 [2]上海交通大学附属儿童医院(上海市儿童医院)脑电图室,200040

出　　处：《临床神经病学杂志》2013年第2期108-110,共3页Journal of Clinical Neurology

基　　金：中国抗癫痫协会2012癫痫科研基金(2011003)

摘　　要：目的研究剥夺睡眠脑电图(EEG)对儿童精神运动性癫痫的诊断价值及其影响因素。方法对110例常规EEG检查阴性的精神运动性癫痫患儿进行剥夺睡眠EEG检查;比较剥夺睡眠EEG检查阳性与阴性患儿的有关临床资料;并对有关指标作多因素Logistic回归分析。结果睡眠剥夺EEG检查阳性62例(56.4%)、阴性48例(43.6%)。与睡眠剥夺EEG阴性组相比,阳性组有缺氧窒息史的比率显著增高,有发作诱因的比率和癫痫的发作频率明显降低,发作时间明显延长(P<0.05～0.01)。多因素Logistic回归分析显示,发作诱因、发作频率和发作时间是影响睡眠剥夺EEG阳性率的相关因素(P<0.05～0.001)。结论剥夺睡眠EEG可提高儿童精神运动性癫痫的诊断率,癫痫的发作诱因、发作频率和发作时间均为影响其阳性率的因素。Objective To research the diagnostic value and its influence factors of sleep-deprived electroencephalogram （EEG） on pediatric psychomotor epilepsy. Methods One hundred and ten conventional EEG negative children with psychomotor epilepsy were examined by sleep-deprived EEG. The relevant clinical data were compared between children with positive and negative sleep-deprived EEG. And the relevant indicators were performed with multivariate Logistic regression analysis. Results The sleep-deprived EEG examination was positive in 62cases （56.4%） , and negative in 48 cases （43.6%）. Compared with sleep-deprived EEG negative group, the rate of hypoxic asphyxia in positive group was significantly increased, the rate of precipitating factors and episodes frequency was significantly decreased, and the episodes duration was significantly extended （P 〈 0. 05 -0.01 ）. The multivariate Logistic regression analysis showed that precipitating factors, episodes frequency and episodes duration were related factors to influent positive rate of sleep-deprived EEG（ P 〈 0. 05 - 0. 001 ）. Conclusion Sleep-deprived EEG can increase the diagnostic rate of pediatric psychomotor epilepsy ; and the epileptic precipitating factors, episodes frequency and duration are factors to influent its positive rate.

关 键 词：脑电图 精神运动性癫痫 儿童 睡眠剥夺 

分 类 号：R742.1[医药卫生—神经病学与精神病学]