当归白芷汤坐浴联合根治性手术治疗白血病化疗后肛周脓肿的临床分析  

The decoction prescriptions combined with radical surgery in treatment of perianal abscess after leukemia chemotherapy

作　　者：刘炜[1] 刘震[1] 徐蕴杰 关文璞[1] 

机构地区：[1]河北省廊坊市中医医院外科,065000 [2]河北省廊坊市中医医院中药房,065000

出　　处：《中国综合临床》2013年第5期539-542,共4页Clinical Medicine of China

摘　　要：目的对当归白芷汤联合切开内口引流术对白血病化疗后肛周脓肿患者的临床治疗效果进行探讨和分析。方法选取100例白血病化疗后肛周脓肿患者随机分为治疗组和对照组，治疗组采用当归白芷汤联合切开内口引流术治疗，对照组采用高锰酸钾液联合切开内口引流术治疗。治疗后观察并记录疗效以及疼痛缓解情况。治疗后随访3年记录复发和瘘管形成情况。结果治疗组和对照组的治愈率分别为90．0％和72．0％，两组间差异有统计学意义（χ2=10．52，P〈0．05）。治疗1周后，治疗组VAS疼痛评分为（2．2±0．4）分，明显低于对照组（4．7±1．2）分（t=14．62，P〈0．01）。治疗组和对照组患者愈合时间分别为（13．4±9．3）d和（19．8±11．6）d，比较差异有统计学意义（t=4．95，P〈0．05）。经3年随访治疗组患者复发率为2．0％，明显低于对照组（22．0％）（χ2=18．93，P〈0．01），治疗组的瘘管形成率为2．0％，明显低于对照组（26．0％），差异有统计学意义（χ2=23．92，P〈0．01）。结论中药当归白芷汤联合切开内口引流术治疗白血病化疗后肛周脓肿，疗效显著并能够有效缓解患者疼痛，值得临床推广。Objective To evaluate the Chinese decoction prescriptions combined with incision drainage operation in treatment of perianal abscess after leukemia chemotherapy. Methods One hundred cases of perianal abscess after leukemia chemotherapy were randomly divided into two groups, treatment group （ Chinese decoction prescriptions combined with incision drainage operation） and control group（ potassium permanganate combined with incision drainage operation）. Observe and record the efficacy and ache alleviated after treatments, recurrences were followed up in and 3 years. Results After the treatments, the total effective rate was 90.0% in the treatment group, significantly more than control group （72. 0% ）, the difference was significant （χ2 = 10. 52, P 〈0. 05）. And treatment after a week the VAS score in the treatment group and control group were（2. 2 ±0. 4） and（ 4.7±1.2）,（t=14.62,P〈0.05）.The healing time were（13.4±9.3） d and（19.8 ±11.6） d,（t= 4. 95, P 〈 0. 05 ）. After 3 years follow-up the recurrence rate and fistula formation rate in the treatment group and control group were 2.0% and 2.0% ,22.0% and 26.0%, （χ2 = 18.93 and 23.92, P 〈 0.01 ）. Conclusion Chinese decoction prescriptions could collaborative incision drainage operation treatment of perianal abscess after leukemia chemotherapy, effective and safe, suitable for extensive application and promotion.

关 键 词：当归白芷汤 切开内口引流术 白血病 肛周脓肿 

分 类 号：R733[医药卫生—肿瘤]