彝族中老年人干眼症与正常眼结膜囊细菌状况对照研究  

Bacterial Profiles in Conjunctival Sac of Dry Eyes and Normal Eyes in Middle-and Old-aged Yi Populations

作　　者：张悦[1] 刘治容[1] 陈辉[1] 樊映川[1] 多吉 郑红 王光进[3] 李玉婵[4] 嘉初丹巴[2] 泽汪格玛 

机构地区：[1]四川省医学科学院.四川省人民医院眼科,成都610072 [2]四川省甘孜藏族自治州州人民医院眼科,康定626000 [3]泸州医学院附属中医院,泸州646000 [4]四川省自贡市第四人民医院眼科,自贡643000 [5]四川省甘孜藏族自治州州人民医院检验科,康定626000

出　　处：《四川大学学报（医学版）》2013年第3期410-413,488,共5页Journal of Sichuan University(Medical Sciences)

基　　金：四川省卫生厅科学研究项目(No.080302)资助

摘　　要：目的比较彝族中老年人干眼症与正常人眼结膜囊细菌状况。方法筛查出九龙县两个彝族聚居点的老年人群中干眼症70人140眼,刮取下睑结膜囊分泌物进行细菌培养分离鉴定。以同一人群中正常人66人132眼作为对照组进行分析对比。结果干眼症组结膜囊细菌阳性率72.1%(101/140),正常组阳性率67.4%(89/132),差异无统计学意义(P=0.397)。两组间不同性别之间差异无统计学意义(P>0.05)。干眼症95.2%(98/103)为革兰阳性菌,正常人群91.1%(82/90)为革兰阳性菌;优势菌种均为表皮葡萄球菌和棒状杆菌,其构成比差异无统计学意义(P>0.05);干眼症组与正常组中单菌与多菌共存构成比、菌种平均数差异均无统计学意义(P>0.05)。结论彝族老年人干眼症与正常人结膜囊细菌阳性率差别不明显;两组结膜囊细菌以革兰阳性菌为主;优势细菌种属及其构成比相似,均为结膜囊正常菌群。Objecitve To compare the bacterial profiles in conjunctival sac of dry eyes and normal eyes in Yi people aged 40 years or old. Methods A cross-sectional survey was conducted with standardized training and protocol. A total of 140 dry eyes of 70 individuals from Yi people in Jiulong county underwent ophthalmological examinations. The secretions of the inferior palpebral conjunetival sac were embroeated and inoculated on blood plates for 48 hours. The bacteria were separated and identified. Another 132 normal eyes from 66 Yi individuals were examined as controls. Results Bacterial positive cultivations were found in 72.1% （101/140） of dry eyes and 67.4% （89/132） of normal eyes, respectively. The difference was not statistically significant （P=0. 397）. No gender difference in the bacterial positive rates was found either. Gram-positive bacteria were the main bacteria in both dry eyes （95.2%, 98,/103）and normal eyes （91.1%, 82/90）, predominantly staphylococcus epidemids and corynebacterium. There were no statistical differences in the constituents of bacteria in Gram classification and numbers of bacteria between dry eyes and normal eyes （P〉0.05）. Conclusion The bacterial profile in conjunctival sac of dry eyes is similar to that of normal eyes in Yi people aged 40 years or over. Gram-positive bacteria are the main bacteria.

关 键 词：结膜囊 细菌 干眼症 彝族 

分 类 号：R777[医药卫生—眼科]