矿物粉尘溶解行为的电镜研究及其生物化学意义  

SEM Study of the Dissolving Behavior of Mineral Dusts and Its Biochemical Significance

作　　者：刘福生[1] 董发勤[1] 李国武[1] 冯启明[1] 

机构地区：[1]西南工学院矿物材料及应用研究所,四川绵阳621002

出　　处：《岩石矿物学杂志》2000年第3期234-242,共9页Acta Petrologica et Mineralogica

基　　金：国家自然科学基金项目!(项目编号 :4 950 2 0 2 5)的资助

摘　　要：本文对用Gamble溶液、有机酸及无机强酸溶解后的矿物粉尘残余物进行了扫描电子显微镜分析。结果表明 ,矿物纤维粉尘纤维变短、长径比减小、柔性减弱、端部变圆 ,部分溶解成串珠状 ;粗大颗粒松散塌陷 ,表面粗糙度增加 ;片状粉尘变碎变细 ;硅酸盐矿物粉尘具有向以SiO2 为主要成分的纳米级近球形颗粒转化的趋势。故提出在纳米级别上研究粉尘致病机理是非常有价值的。Minerals dusts are harmful to human health when a great amount of dusts, especially fibrous dusts, are taken into a human body. Through the digestive system, these dusts will come into the stomach and then are dissolved by acid and no influence will be exerted on health, but when dusts come into the breathing system, their reaction with the human body is very complex. They can move, be deposited, penetrate or be dissolved, and may cause cancer or silicosis. The dissolving process is simulated in this study. SEM analysis was made of the residues of mineral dusts dissolved in the simulated human body fluid——Gamble solution, organic acid and inorganic strong acid. The results have revealed the following: the fibers of the fibrous mineral dusts become shorter, the length diameter ratio is reduced, the flexibility weakens, the ends become rounded and a part of fibers are dissolved and become strings of beads; the coarse grains are loose and collapsed and their surface roughness increases; planar dusts become granulated and fine; silicate mineral dusts have a tendency to be dissolved into subspherical nanometer_sized grains composed dominantly of SiO 2. The authors further propose that it is of great value to study of the nosogenesis by dusts on the nanometer size.

关 键 词：矿物粉尘 模拟体液 扫描电镜 生物化学 溶解 

分 类 号：R135.2[医药卫生—劳动卫生]