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机构地区:[1]白求恩医科大学第一临床学院儿科,吉林长春130021 [2]吉林省肿瘤医院,吉林长春130000 [3]吉林省靖宇县医院,吉林靖宇县135200
出 处:《临床肝胆病杂志》2000年第3期174-175,共2页Journal of Clinical Hepatology
摘 要:为探讨乙肝疫苗接种以来儿童肝硬化的发病情况,对29例小儿肝硬化临床资料进行回顾研究。患病年龄最小3个月,最大15岁,病程3个月至6年不等。其中,乙肝病毒标志物阳性者9例(31%),肝豆状核变性8例(27.1%),提示乙型肝炎肝硬化的发病率仍占首位;小儿肝硬化早期不易发现,定期全面认真体检可减少隐匿性肝硬化的发生。另外,改善营养状况、控制感染,也是减少儿童肝硬化发生的重要环节。To investigate the morbidity and harmfulness of cirrhosis in children,clinical analysis was performed retrospectively.in 29 hospitalized patients with cirrhosis in children from Oct.1982 to Oct.1999 of them,youngest patients was only 3 months and the eldest was 15 years-old.The courses of illness varied from 3 months to 6 years.Of all 29 cases,9(31.0%) were positive for he patitis B virus marker,8(27.1%) showed Wilson disease,and 8(27.1%)were manifested by congenital malformation of bile duct.The cirrhosis caused by hepatitis B is still the most common.The results suggest that the cirrhosis in children was not easily be found at early stage and more attention should be paid to careful physical examination.For prevention.Further more,control of infection and improvement of the nutritional status are of very importance for reducing the cirrhosis morbidity.
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