全盆腔放疗加后程三维适形放射治疗中晚期宫颈癌疗效观察  

Clinical study of middle and advanced uterine cervix cancer treated with 3DCRT plus pelvic irradiation

作　　者：赵彩霞 付曦 郭翠华 

机构地区：[1]南充市中心医院肿瘤防治中心,四川南充637000

出　　处：《四川医学》2013年第3期351-353,共3页Sichuan Medical Journal

摘　　要：目的观察全盆腔放射治疗加后程三维适形放射治疗(3DCRT)不能手术的中晚期宫颈癌临床疗效。方法45例确诊为ⅡB～ⅢB期宫颈癌患者,先采用模拟机定位、全盆腔前后两野对穿照射,然后采用体模固定、CT模拟定位勾画肿瘤靶区(GTV)和临床靶区(CTV)三维适形放疗。结果近期总有效率91.1%,ⅡB期、Ⅲ期3年生存率分别为73.1%、63.2%。早晚期放疗反应均为Ⅰ～Ⅱ级。结论采用全盆腔放疗加后程三维适形放射治疗对中晚期宫颈癌有较好的局控率与生存率,不良反应轻,患者易耐受,且操作易行。Objective To investigate the clinical curative effect in middle and advanced-stage uterine cervix cancer pa- tients who could not operated treated with three dimensional conformal radiation therapy（3DCRT） plus pelvic irradiation. Meth- ods The records of 45 case patients with ⅡB -Ⅲ B stage cervical cancer were treated with 3DCRT plus pelvic irradiation. Re- suits Total efficiency （ CR ＋ PR） was 91.1%. The 3 year survival rate of Ⅱ B and Ⅲ stage was 73.1% and 63.2% , respec- tively. All complications were considered Ⅰ-Ⅱ grade. Conclusion 3DCRT plus pelvic irradiation is a good method to treat middle and advanced cervical cancer. It can be easily endured with its convenient operation, little adverse reaction, satisfactory survival rates and local control.

关 键 词：宫颈癌 放射治疗 三维适形 

分 类 号：R737.33[医药卫生—肿瘤]