精神分裂症患者述情障碍与执行功能及情绪障碍的关系  

Alexithymia in schizophrenia:association with executive function and emotional disorder

作　　者：蔡菡[1] 李泽爱[2] 刘寰忠[2] 陈学全[1] 

机构地区：[1]安徽医科大学医学心理学系,合肥230032 [2]安徽省精神卫生防治中心

出　　处：《精神医学杂志》2013年第2期107-110,共4页Journal of Psychiatry

摘　　要：目的探讨精神分裂症患者的述情障碍与执行功能和焦虑、抑郁情绪之间的关系。方法用多伦多述情障碍20个条目量表(TAS-20)、威斯康星卡片分类测试(WCST)、焦虑自评量表(SAS)和抑郁自评量表(SDS)对150例精神分裂症患者分别进行述情障碍、执行功能及焦虑和抑郁症状的评定,抽取TAS总分≥62为高分组(38例)和TAS总分≤53为低分组(42例),比较两组的WCST成绩并与TAS-20总分及各因子分进行相关分析。同时将SAS、SDS标准分与TAS-20进行相关分析。结果述情障碍高分组的错误应答数、非持续性错误数、完成第一次分类应答数均高于低分组(P<0.05);而高分组的完成分类数、正确应答数、正确应答百分数、概念化水平应答率则明显低于低分组(P<0.01);相关分析显示,TAS-20的总分及因子分与WCST成绩呈负相关(P<0.05),TAS-20的总分及因子分与SAS、SDS标准分呈正相关(P<0.05)。结论精神分裂症患者的述情障碍与执行功能损害、负性情绪密切相关。Objective To explore the alexithymia and its relationship with executive function, anxiety and depressive emotion in patients with schizophrenia. Methods 150 schizophrenic patients were assessed with Toronto Alexithymia Scale-20 （TAS-20）, Wisconsin Card Sorting Test （WCST）, Self-rating Anxiety Scale （SAS）, Self-rating Depression Scale and Depression Status Inventory （SDS）. Patients were divided into high alexithymia group （38 cases with score of TAS-20 ≥ 62 ） and low alexithymia group （42 cases with score of TAS-20 ≤53 ）. Score of WCST was compared between the two group. The relationship between scores of WCST, SAS, SDS and TAS-20 were detected by using correlation analysis. Results Number of wrong response, non-preservative errors and failing to keep fixed posture was significantly higher in high alexithymia group than those in low alexithymia group （P 〈 0.05 ）. While the number of correct classification, number of correct response, the percentage of correct response and response rate of conceptualization was significantly lower in high alexithymia group than those in low alexithymia group （P 〈 0.01 ）. The total score and factor scores of TAS-20 were significantly negatively correlated with WCST performance （ P 〈 0.05 ）, and were significantly positively correlated with standard scores of SAS and SDS （ P 〈 0.05 ）. Conclusion The level of alexithymia is closely correlated with the impairment of executive functioning and the negative emotion in schizophrenic patients.

关 键 词：精神分裂症 述情障碍 执行功能 抑郁 焦虑 

分 类 号：R749.3[医药卫生—神经病学与精神病学]