双氯芬酸钠滴眼液在Toric人工晶状体植入手术围手术期的应用  

Clinical assessment of diclofenac sodium eye drops in toric intraocular lens implantation

作　　者：罗艳[1] 冯劼[1] 鲁铭[1] 程旭康[1] 

机构地区：[1]中国湖北省武汉市第一医院眼科,430000

出　　处：《国际眼科杂志》2013年第5期880-882,共3页International Eye Science

基　　金：武汉市卫生局科研基金资助项目(武卫【2009】76号No.WX09C03)~~

摘　　要：目的:观察双氯芬酸钠滴眼液在Toric人工晶状体植入围手术期应用的疗效。方法:将2011-01/2012-02的37例38眼合并角膜散光的白内障患者随机分为两组,试验组(18例19眼),对照组(19例19眼)。行超声乳化白内障吸出及Toric人工晶状体植入术治疗。试验组在对照组用药基础上,术前3d及术后第1d加用1g/L双氯芬酸钠滴眼液,4次/d。两组患者分别于术中记录患者的配合程度,术后1,3,7d;1,3mo观察眼部炎性反应。结果:术中配合程度试验组平均1.53±0.62,明显优于对照组(2.40±0.88),采用t检验进行组间比较,差异有统计学意义(P<0.05)。术后1d试验组局部症状评分为1.65±0.75,明显低于对照组(2.32±1.23),采用t检验进行组间比较,差异有统计学意义(P<0.05)。结论:在超声乳化白内障吸出及Toric人工晶状体植入术围手术期短期应用双氯芬酸钠滴眼液,安全性可,能够减轻患者在手术过程中的刺激反应,提高患者手术中的配合程度,有效减轻患者的围手术期炎症反应。AIM： To evaluate the application of diclofenac sodium eye drops in toric intraocular lens implantation. METHODS： From January 2011 to February 2012, 38 eyes of 37 patients, who underwent toric intraocular lens implantation in this hospital, were randomly divided into diclofenac sodium eye drops group （trial group） and control group. Patient＇s degree of cooperation during surgery and inflammation postoperation after 1 day, 3,7, days, 1 month and 3 months were evaluated. RESULTS： Patient＇s degree of cooperation during surgery in the trial group （1.53±0.62） was significantly better than in the control group （2.40±0.88, P〈0.05）. Inflammation reaction was gentle in the trial group 1 day postoperatively. CONCLUSION： Diclofenac sodium eye drops used during toric intraocular lens implantation can obviously alleviate eye irritation, and increase the cooperation of patients.

关 键 词：双氯芬酸钠 白内障 环曲面 人工晶状体 

分 类 号：R779.66[医药卫生—眼科]