第二代结肠胶囊内镜诊断结肠病变的初步研究  

The clinical preliminary study of second generation colon capsule endoscopy

作　　者：宋军[1] 胡耿诚[1] 谢小平[1] 刘俊[1] 侯晓华[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院消化内科,武汉430022

出　　处：《中华消化内镜杂志》2013年第5期249-252,共4页Chinese Journal of Digestive Endoscopy

摘　　要：目的初步探讨第二代结肠胶囊内镜在结肠疾病诊断中的作用。方法14例志愿者在完成肠道准备后采用第二代结肠胶囊内镜行结肠检查，观察肠道清洁度，胶囊通过胃、小肠、结肠的时间，胶囊内镜检出病变、胶囊排除以及检查过程中副反应等情况。结果14例受检的志愿者中，肠道清洁度良好10例，胃平均通过时间（82±39）min，小肠平均通过时间（121±73）min，结肠平均通过时间（310±125）min。10例存在胃部病变，包括糜烂性胃炎和胃溃疡；6例存在小肠病变，包括小肠息肉、回肠溃疡和小肠隆起性病变；7例存在结肠病变，包括结肠息肉、结肠隆起性病变和内痔。13例受检志愿者胶囊在480min内排出。检查过程中均未出现严重不良反应。结论第二代结肠胶囊内镜可观察结肠黏膜是否存在病变，用于结肠疾病的临床筛查和诊断效果较好。Objective To investigate the diagnositic role of second generation colon capsule endos- copy in colorectal diseases. Methods After colon preparation procedure, fourteen volunteers were observed with second generation colon capsule endoscopy. During the examination, stomach and small bowel transit time, the colorectal examination time and the positive founding were recorded. Capsule excretion rate, the colon cleaning level and rate of adverse events also were assessed. Results Colorectal diseases including colon polyp, colon protrusion lesion and internal hemorrhoid were found in 7 volunteers. Stomach diseases including erosive gastritis and gastric ulcer in 10 volunteers. Small bowel diseases including small bowel pol- yp, ileum ulcer and small bowel protrusion lesion in 6 volunteers. Thirteen capsule were excreted within 480 minutes. The average colorectal examination time was 310± 125 minutes. The average stomach and small bowel transit time were 82± 39 minutes and 121± 73 minutes, respectively. The overall colon cleanliness was adequate in 7 patients. There are no severe adverse events during the examination. Conclusion The second generation capsule endoscopy can observe the eolorectal mucosal changes and it might be considered as an adequate tool for colorectal diseases screening and diagnosis.

关 键 词：胶囊内窥镜 结肠 结肠疾病 普查 

分 类 号：R57[医药卫生—消化系统]