幽门螺旋杆菌感染与反流性食管炎的相关性分析  

CorrelativeAnalysis of H. pylori and Reflux Esophagitis

作　　者：邹伟清[1] 

机构地区：[1]南方医科大学附属深圳宝安医院消化内科,深圳518000

出　　处：《中国医药导刊》2013年第3期402-402,404,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:针对幽门螺旋杆菌感染与反流性食管炎的发生进行相关性分析。方法:选取2011年2月至2012年4月来我院就诊的150例反流性食管炎患者作为观察组,并选择同期的150例慢性浅表性胃炎患者作为对照组,比较两组患者的幽门螺旋杆菌阳性率,并对幽门螺旋杆菌感染与反流性食管炎的程度进行相关性分析。结果:观察组和对照组幽门螺旋杆菌阳性率分别为44.00%和64.00%,有明显差异(P<0.05),幽门螺旋杆菌阴性的中、重度反流性食管炎的发生率与幽门螺旋杆菌阳性相比,略升高(P<0.05)。结论:反流性食管炎患者幽门螺旋感染阳性率较低,且幽门螺旋杆菌阳性的反流性食管炎程度较轻,可能原因是幽门螺旋杆菌可能对反流性食管炎的发生有一定的保护作用。Objective：To study the correlative analysis of H.pylori and reflux esophagitis.Method：Atotal of 150 patients with reflux esophagitis were enrolled into this study in our hospital between Feb,2011 and Apr,2012 as observation group.And a total of 150 patients with chronic superficial gastritis were also enrolled into this study as control group.The positive rates of H.pylori in the two groups were compared and analyzed.And we also conducted correlative analysis of H.pylori and reflux esophagitis in this study.Results：The positive rate of H.pylori was 44.00% and 64.00%,respectively.The incidence rate of moderate and severe reflux esophagitis with no H.pylori infection was higher than that of patients with H.pylori infection（P0.05）.Conclusion：The incidence rate of reflux esophagitis was lower and the degree of reflux esophagitis with H.pylori infection was also lower.The possible reason was that H.pylori has the protective role in the occurrence of reflux esophagitis.

关 键 词：幽门螺旋杆菌 反流性食管炎 相关性 

分 类 号：R571[医药卫生—消化系统]