加强干眼抗炎治疗的临床研究  

Emphasizing clinical investigation on anti-inflammatory therapy of dry eye

作　　者：刘祖国[1] 刘靖[1] 杨文照[1] 

机构地区：[1]厦门大学眼科研究所福建省眼科与视觉科学,361201

出　　处：《中华实验眼科杂志》2013年第5期417-420,共4页Chinese Journal Of Experimental Ophthalmology

摘　　要：炎症是一种防御反应，是干眼最常见的病理表现，而过度的炎症反应也是引起干眼常见的发病因素以及干眼进展的重要原因。抗炎药物是治疗干眼的常用药物，目前其作用机制已逐渐明确。抗炎药物的应用对缓解干眼的炎症反应具有一定的疗效，但也具有一定的不良反应，因此干眼患者局部抗炎药物的应用及其疗效的评价需要实施大样本、随机对照的多中心临床试验，以明确不同抗炎药物对不同类型干眼的治疗效果，为规范干眼的抗炎治疗提供依据。Inflammation is a defensive reaction and the most common pathological manifestation of dry eye. In addition, excessive inflammatory response is considered to be the most common pathogenic factor and main cause of dry eye. Currently, the active mechanism of anti-inflammatory drugs has been well-known, and topical anti- inflammatory therapy for dry eye is exerting a role at certain extend. However, some adverse responses of these drugs are emerging during the treating procedure. Therefore, it is emphasized that a large sample size of and multicenter randomized-controlled clinical trial is needed to identify the different effects of various anti-inflammatory drugs for different types of dry eye diseases,which will offer a basis for standardized anti-inflammatory treatment for dry eye.

关 键 词：干眼 抗炎疗法 多中心大样本随机对照临床试验 

分 类 号：R777[医药卫生—眼科]