经筋排刺法治疗周围性面瘫多中心大样本随机对照试验研究  

Multiple-center and large-sample randomized controlled trials of Jingjin needling method in the treatment of the periphery facial nerve paralysis

作　　者：李桂平[1] 李妍[1] 袁军[2] 薛艳艳[3] 李瑛[4] 刘立安[5] 

机构地区：[1]天津中医药大学第一附属医院,300193 [2]河北省中医院 [3]中国人民解放军第四六四医院 [4]成都中医药大学针灸学院 [5]青岛海慈医疗集团

出　　处：《中华针灸电子杂志》2012年第2期6-10,共5页Chinese Journal of Acupuncture and Moxibustion（Electronic Edition）

基　　金：国家”十一五”科技支撑计划项目（2006BA112B03-2）

摘　　要：目的观察经筋排刺法治疗周围性面瘫（PFNP）的临床疗效和最佳介入时机。方法采用多中心大样本随机对照试验方法，根据纳入和排除标准将2007年12月至2009年8月在成都、天津、青岛3个临床研究中心的360例贝尔面瘫患者随机分为分期针刺组和经筋排刺组，针刺1次，d，5次为1疗程，共治疗4个疗程。于入组时、治疗1，2，3和4疗程以及治疗后1个月和3个月随访时，分别采用House—Braekmann分级量表、面部残疾指数量表、面神经麻痹程度分级评分表等进行疗效评价。所得数据采用SAS9．1．3和SPSS13．0统计分析软件进行分析进行t检验，X。检验和秩和检验，P≤0．05（即d=0．05）被认为差异有统计学意义。结果经筋排刺治疗周围性面瘫的痊愈率、显效率和总有效率分别为42．7％，28．1％和85．4％，鼓索以下损伤的的痊愈率和显效率分别为49．6％和29．6％，较鼓索以上（痊愈率和显效率分别为30．2％和25．4％）好，可改善周围性面神经麻痹患者的面部功能和社会功能；针刺治疗的疗效在周围性面瘫患者急性期和静止期介入（痊愈率分别为41．8％和45．8％）优于恢复期介入（总有效率为38．1％）。结论经筋排刺法治疗PFNP临床疗效肯定，急性期和静止期介入针刺治疗的效果优于恢复期介入。Objective To observe the clinical efficacy and best intervention time of Jingjin needling method for periphery facial nerve paralysis（PFNP）. Methods A total of 360 patients from clinic and hos- pitalization of three centers： Cheng-du, Tianjin and Qingdao from December 2007 to August 2009, collected to be randomly assigned to acupunture group by stages and Jingjin needling group with inclusion and exclusion criteria by large sample multi-center randomized controlled trials method.The therapeutic effects were evaluated with House-Brackmann rating scale,the facial disability index scale and facial paralysis grading-score table at intake, treatment afterl, 2, 3, 4 course of treatment, and the ending of 1 and 3 months after all four courses, which data used statistical package SAS 9.1.3 and SPSS13.0 t test, X2 test and the rank sum test, taking P≤0.05 for the difference was statistically significant. Results The cure rate, effective rate and total effective rate of Jingjin needling method for PFNP was 42.7%, 28.1% and 85.4%, respectively. The cure rate and effective rate of the under tympanic nerve＇s acupuncture treat （49.6% and 29.6%） are more effective than that above tympanic nerve＇s （30.2% and 25.4%）, facial and social function improved. The best intervention time of Jingjin needling method for the PFNP were acute and resting stage （cure rate were 41.8% and 45.8%）, rather than restoration stage （cure rate was 38.1%）. Conclusion It might be an effective method to treat PFNP in acute and resting stage better than restoration stage.

关 键 词：面神经麻痹 治疗结果 经筋排刺法 介入时机 

分 类 号：R775[医药卫生—眼科]