蕲蛇酶治疗急性脑梗死临床观察  

Clinical analysis of treating acute cerebral infarction with the enzyme of the long-node pit viper

作　　者：刘宪平 张瑛[2] 

机构地区：[1]河南省信阳市中心医院,464000 [2]上海第二医科大学附属仁济医院神经内科,200001

出　　处：《中国急救医学》2000年第9期529-530,共2页Chinese Journal of Critical Care Medicine

摘　　要：目的　观察蕲蛇酶治疗急性脑梗死的疗效及安全性。方法　选择急性脑梗死患者 6 2例 ,应用蕲蛇酶 0 75U加入生理盐水 2 5 0ml中静脉点滴 7天 ,并以低分子右旋糖酐 5 0 0ml加复方丹参注射液 16ml静脉点滴 14天的 6 2例急性脑梗死患者作对照。结果　治疗组总有效率 85 5 % ,明显高于对照组的 6 7 7% (P <0 0 5 ) ,未发现不良反应。结论　蕲蛇酶治疗急性脑梗死能显著改善临床症状 ,降低致残率 ,安全性高。Objective To observe the curative effect and the safety of the treatment.Methods The study was carried out among 62 acute cerebral infarction patients (38 male, 24 female), whose ages from 48～80.We put 0.75 U snake enzyme into 250 ml normal saline injection for intravenous dripping for seven days. At the same time, another 62 acute cerebral infarction patients which was control group get 14 days intravenous dripping with 500 ml low-molecular dextran and 16 ml salvia miltiorrhiza compound injection.Results The general effective rate of the treating group was 85.5%, which was significantly higher than that of the control group (67.7%) (P<0.05). In this study we didn't find any obvious bad effects. Conclusions Treating acute cerebral infarction with the enzyme of the long-mode pit viper can significantly improve the patients' clinical symptoms, reduce the rate of deformity. This treatment has high safety. [

关 键 词：蕲蛇酶 急性脑梗死 药物疗法 安全性 

分 类 号：R743.33[医药卫生—神经病学与精神病学]