以盆腔肿物为表现的腹膜假黏液瘤7例诊治分析  

Diagnosis and treatment of pseudomyxoma peritonei presented as pelvic neoplasms:report of 7 cases

作　　者：叶璐[1] 吴良芝[1] 张艺[1] 冯亦军[1] 马奔[2] 

机构地区：[1]广东省第二人民医院妇科,广东广州510317 [2]广州市第一人民医院妇产科,广东广州510182

出　　处：《广州医学院学报》2013年第1期53-56,共4页Academic Journal of Guangzhou Medical College

摘　　要：目的:探讨以盆腔肿物为表现的腹膜假黏液瘤(pseudomyxoma peritonei,PMP)的临床表现和诊治。方法:收集2007年1月至2012年7月广东省第二人民医院和广州市第一人民医院妇产科的7例腹膜假黏液瘤患者.通过对该7例以盆腔肿物为表现的PMP病例资料,分析其临床特点、影像学特征、诊断和治疗、随访和预后。结果:7例患者临床主要表现均为腹胀、腹痛,术前超声检查、CT、MRI提示盆腔包块和不均质腹水.肿瘤标记物有不同程度升高,所有患者均经手术病理确诊为腹膜假黏液瘤,术后辅助治疗包括化疗.术后随访率100%。结论:女性PMP在临床上容易误诊为盆腔肿物,从而误诊和延误治疗.通过术前腹部B超、CT、MRI、肿瘤标记物检查结合腹腔穿刺细胞学检查、术中快速冰冻病理检查,可以提高诊断率。及时与正确处置对患者的预后和生存期的提高都有重要的意义。Objective：To investigate the clinical manifestations and treatment of pseudomyxoma peritonei （PMP） presented as pelvic tumor. Methods： We retrospectively analyzed the clinical profiles of 7 patients of PMP presented as pelvic masses who were admitted to Guangdong Second People＇s Hospital and Guangzhou First People＇s Hospital between January 2007 and July 2012. This entailed subsequent analysis on the clinical characteristics, imaging features, diagnosis, treatment and prognosis of PMP. Results： The 7 cases predominantly presented with abdominal distension and tenderness, and pelvic mass and heterogeneous peritoneal aseites as indicated by uhrasonography, computed tomography and magnetic resonance imaging preoperatively. Increased levels of tumor markers may be noticeable. All cases with confirmed pathology-diagnosed PMP were treated with chemotherapy as an adjuvant therapy and were not loss of follow-up. Conclusion ： The fact that PMP in females is readily misdiagnosed as pelvic masses, could have accounted for the delay of treatment. The diagnostic yield may be improved by the addition of abdominal puncture cytology and frozen section pathological examination on the basis of ultrasonography, computed tomography and magnetic resonance imaging preoperatively. Appropriate and timely diagnosis and treatment is of significance to improve the prognosis of PMP.

关 键 词：卵巢 腹膜 假黏液瘤 诊断 治疗 

分 类 号：R735.35[医药卫生—肿瘤]