Th17细胞与肝脏疾病关系的研究进展  

Th17 cells and liver diseases

作　　者：薛芝敏[1] 姚冬梅[1] 

机构地区：[1]河北医科大学第二医院消化内科,河北省石家庄市050000

出　　处：《世界华人消化杂志》2013年第13期1185-1190,共6页World Chinese Journal of Digestology

摘　　要：近年来研究发现,辅助性T细胞17(Thelper cells 17,Th17)与病毒性肝炎、自身免疫性肝病以及脂肪性肝病等多种肝病的发生发展密切相关.Th17细胞是新发现的CD4+T细胞亚群,与调节性T细胞(regulatory T cells,Treg)、T h1细胞及T h2细胞在分化发育上相互制约,在功能上存在着拮抗或协同的复杂关系,研究Th17细胞在多种肝病发生发展中的作用有助于进一步探索肝病的发病机制及治疗方法.In recent years,it has been demonstrated that T helper cells 17（Th17） are closely related to the occurrence and development of many kinds of liver diseases such as viral hepatitis,autoimmune liver diseases and fatty liver diseases.Th17 cells are a new CD4＋ T cell subset,which can interact with Th1,Th2 and Treg cells.There exists complex antagonistic or collaborative relationship among these cells.Understanding the role of Th17 cells in liver diseases will help explore the pathogenesis and treatment of these diseases.

关 键 词：TH17细胞 白介素17 免疫反应 肝脏 

分 类 号：R575[医药卫生—消化系统]