兰索拉唑联合莫沙比利治疗反流性食管炎的临床疗效观察  

To evaluate the clinical efficacy of lansoprazole combined mosapride for reflux esophagitis

作　　者：杨灿宇[1] 邓丽颖[1] 

机构地区：[1]辉县市人民医院,河南辉县453600

出　　处：《健康大视野（医学版）》2012年第1期5-6,共2页Health Horizon:Medical Science Fascicule

摘　　要：目的观察兰索拉唑联合莫沙比利治疗反流性食管炎（RE）的，临床疗效，探讨药物治疗反流性食管炎的有效方法。方法选择反流性食管炎100例，随机均分为观察组和对照组，观察组采用奥美拉唑联合莫沙必利治疗，8周后统计2组患者的临床疗效及用药不良反应。结果治疗8周后，2组患者总有效方面比较具有统计学意义（P〈0．05）；不良反应方面比较均无显著性差异（P〉0．05），且不良反应均为一过性。结论药物治疗RE时，应选择兰索拉唑联合莫沙必利治疗，可提高临床疗效。Objective To evaluate the clinical efficacy of lausoprazole combined mesapride for reflux esophagitis and explore the effective therapy for reflux esophagitis. Methods A total of 100 reflux esophagitis cases were equally randomized to either trial group receiving lansoprazole plus mosapride or control group receiving lansoprazole. After treatment of 8 weeks, the clinical efficacy and adverse drug reactions in the two groups were recorded. Results There were statistical significant differences in total effective rate between the two groups after 8 - week treatment（ P 〈 0.05）, but the differences in side effects were nonsignificant（ P 〉 0.05）and the adverse drug reactions were transient. Conclusions Treatment of reflux esophagitis with lansoprazole plus mosapride results in improved clinical efficacy.

关 键 词：兰索拉唑 莫沙必利 反流性食管炎 临床疗效 

分 类 号：R571[医药卫生—消化系统]