37例少突星形细胞瘤临床及MRI表现与病理分级关系  

The Relationship Between Clinical and MRI Manifestations and Pathologic Grade in Oligoastrocytic Tumour:Report of 37 Cases

作　　者：卢晓丹[1] 陈燕萍[1] 周和秀[1] 谭健儿[1] 易云平[1] 

机构地区：[1]南方医科大学南方医院影像中心,广州510515

出　　处：《临床放射学杂志》2013年第5期617-622,共6页Journal of Clinical Radiology

摘　　要：目的探讨少突星形细胞瘤的临床、MRI表现及其与组织病理学分级的关系。方法搜集并统计37例经手术及病理证实的少突星形细胞瘤患者主要的临床资料(性别比例、头痛头晕发生率、癫痫发生率)并观察其MRI主要征象(发病部位、囊变、跨叶生长、水肿、占位效应、出血、环形强化、明显强化),总结MRI图像特点并分析不同指标与肿瘤分级间的关系。结果 37例中,少突星形细胞瘤20例,间变性少突星形细胞瘤17例。额叶14例,颞叶5例,跨叶生长18例。实性者20例,囊实混合性者17例。出血者8例。MRI图像上以长T1、长T2信号为主,增强扫描强化形式多样。统计学分析,WHOⅡ级组与WHOⅢ级组间,癫痫率、囊变率、水肿明显率、占位效应明显率、环形强化率、明显强化率的差异有统计学意义(P=0.017、0.009、0.023、0.008、0.023、0.000);而性别、头痛头晕发生率、生长部位、是否跨叶生长、出血率差异无统计学意义(P=0.100、1.000、0.100、0.746、1.000)。结论少突星形细胞瘤MRI征象中,囊变、水肿明显、占位效应明显、环形强化、明显强化与肿瘤组织病理学分级有关,而性别、头痛头晕发生率、生长部位、是否跨叶生长、出血率与肿瘤组织病理学分级无关。Objective To investigate the clinical manifestations and the MR imaging findings,and analysis the relationship between clinical and MRI manifestation with pathologic grade in Oligoastrocytic tumours（OAs）.Methods Clinical and MRI manifestations of 37 cases of OAs proved by operation and pathology were retrospectively observed and analyzed.The gender ratio,incidence of headache and dizzy,incidence of seizure,the tumor site,cystic degeneration,cross-sectional grew,edema,space occupied effect,hemorrhage,ring enhancement,and enhancement obviously or not were studied.These data were analyzed with pathologic grading to obtain the relationship of MRI findings with tumor pathology classification.Results Among the 37 cases,there was 20 cases of oligoastroytomas（OA/OA2） and 17 cases of Anaplastic Oligoastroytoma（AOA/OA3）.14 cases located in frontal lobes and 5 cases in temporal lobes,with 18 cases in cross-sectional area.Solid masses in 17 cases and mixed cystic-solid masses in 20 cases.Hemorrhage was found in 8 cases.Generally,tumors appeared as low or slightly low signal intensity on T1WI and high or slightly high signal intensity on T2WI,enhancement patterns were miscellaneous.There was statistically significant differences within group of OA2 and group of OA3 in the seizure,cystic degeneration,edema,space occupied effect,ring enhancement and enhancement obviously（P=0.017、0.009、0.023、0.008、0.023、0.000）,but no statistically significant differences in the gender ratio,incidence of Headache and dizzy,the tumor site,cross-sectional area,hemorrhage（P=0.100、1.000、0.100、0.746、1.000）.Conclusion Seizure,cystic degeneration,edema,occupied effect,ring enhancement and enhancement obviously of oligoastrocytic tumours in MR image are related to pathological classification.

关 键 词：少突星形细胞瘤 磁共振成像 组织病理学 WHO分级 

分 类 号：R739.4[医药卫生—肿瘤]