下肢软组织炎性肌纤维母细胞瘤的MRI表现及病理对照(附5例分析)  

MRI and Pathological Features of the Inflammatory Myofibroblastic Tumor in Lower Extremity(With 5 Cases Report)

作　　者：黄国权[1] 余永强[1] 王海宝[1] 

机构地区：[1]安徽医科大学第一附属医院放射科,230022

出　　处：《临床放射学杂志》2013年第5期748-751,共4页Journal of Clinical Radiology

摘　　要：目的通过对下肢软组织炎性肌纤维母细胞瘤(IMT)的MRI表现与病理对照分析,提高对下肢IMT的MRI诊断水平。方法回顾性分析经手术病理证实的5例下肢软组织IMT患者的MRI表现。结果 5例中病变发生于左大腿3例、左足底1例、右大腿1例;MRI表现,肿块呈分叶状,4例主病灶相邻深部肌间隙内见相连小卫星灶;与肌肉信号相比,T1WI肿块以等信号为主,其内或周边见条状稍低信号,T2WI呈混杂高信号为主,内见条状稍低信号;增强后肿块实性部分呈中度或明显不均匀强化,4例见延迟强化,坏死、囊变区小,无强化。病理示肿瘤由梭形细胞及炎症细胞组成,免疫组织化学染色肌源性蛋白阳性表达。结论下肢软组织IMT常累及相邻深部肌间隙形成多发结节灶,T2WI显示瘤内条状低信号的特点,MRI对IMT的定位、定性及鉴别诊断具有一定临床应用价值。Objective To improve the level of MRI diagnosis of the soft tissue IMT in the lower extremity by analyzing MRI and pathological features.Methods The clinical manifestation,pathological features and the MRI appearances of 5 cases IMTs with pathologically confirmed were analyzed retrospectively.Results Five cases were recruited in the study,including the left thigh three cases,left foot one case and the right thigh one case.Lobulated masses with some small satellite masses adjacent to the main mass were seen in deep muscle gap in four cases.Compared with muscle signal,the strip slightly low signal among isointensity mass had been showed on T1WI and mixed high signal on T2WI.The solid parts of mass were moderate or significantly heterogeneous enhancement and delayed enhancement in four cases and no enhancement in the small necrosis,cystic areas.The tumors composed of spindle cells and inflammatory cells and positive muscle-derived protein.Conclusion The soft tissue IMT in lower extremity often involves the deep muscle gap and multiple nodules and the strip of slightly low signal among mass shown on T2WI.MRI is helpful for location,qualification and differential diagnosis of IMT.

关 键 词：软组织肿瘤 肌纤维母细胞瘤 磁共振成像 病理学 

分 类 号：R739.96[医药卫生—肿瘤]