社区老年人轻度认知功能损害危险因素调查  

Investigation and analysis of the risk factors for the community elderly with mild cognitive impairment

作　　者：陈定华[1] 瞿正万[1] 江琦[1] 张明[1] 裴瑜[1] 朱莉娜[1] 孙喜蓉[1] 傅伟忠[1] 杨振东[1] 秦虹云[1] 傅红梅[1] 张洁[1] 袁杰[1] 卢瑛[1] 唐强[1] 孙一颖[1] 

机构地区：[1]上海市浦东新区精神卫生中心,上海200124

出　　处：《中华行为医学与脑科学杂志》2013年第5期413-416,共4页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：上海市浦东新区政府资助项目（PKJ2010-y26）

摘　　要：目的调查轻度认知功能损害（MCI）危险因素对疾病的可能影响程度。方法应用多阶段多层次随机抽样法，采用上门单独问卷调查方式，对4086例上海浦东新区户籍老年人进行流行病学调查，运用Petersen的MCI诊断标准，将老人分成MCI组和正常智力组进行对照，分析危险因素。结果MCI占612例，患病比率为14．98％。文盲患MCI的相对危险度（RR）是初中、高中及大学文化的3．11，3．92及5．13倍；女性是男性的1．382倍；80—89岁组和≥90岁组是60～69岁组的2．987和2．146倍；月收入〈1300元组是〉4000元组的1．698倍，糖尿病组和高血压组是非糖尿病和非高血压组的2．756和2．151倍。Logistic多元回归分析显示：高龄、文化程度低、养老金低、患糖尿病、高血压、高血脂症及吸烟等是危险因素（P〈0．05）。结论社区老人MCI患病比率较高，受多种危险因素明显影响，针对性的早期干预有助于减少该病的发生发展。Objective To investigate the risk factors of mild cognitive impairment （MCI） in community elderly, and discuss the prevention and treatment countermeasures for MCI. Methods The multi-stage and multi- level random sampling method was applied to epidemiological investigation of census register the 4086 elderlies in pudong New area of Shanghai. Using the door questionnaire separately and Petersent diagnostic standard,the elderly were divided into MCI group and normal intelligence group and analysed the risk factors. Results There were 612 patients with MCI in the elderly and the prevalence rate was 14.98%. The MCI relative risk （RR） of illiteracy suffering was 3.11,3.92 and 5.13 times than that of the junior middle school,high school and university culture. Tlae MCI relative risk of women suffering was 1. 382 times than that of men. The MCI relative risk of 80-89 age group and more than 90 age group suffering was 2. 987 and 2. 146 times than that of 60-69 age group. The MCI relative risk of monthly income below 1300 yuan group suffering was 1. 698 times than that of monthly income over 4000 yuan group. The MCI relative risk of diabetes group suffering was 2. 756 times than that of non-diabetes group. The MCI relative risk of hypertension group suffering was 2. 151 times than that of non-hypertension group. Logistic multivariate regression analysis showed that age, low education level, low pensions, diabetes, hypertension, hyperlipidemia and smoking were risk factors（P 〈 0.05）. Conclusion The prevalence of community elderly with MCI is high,which is affected by a variety of risk factors significantly, and early interventions can help to reduce the development of the disease.

关 键 词：轻度认知功能损害 老年人 社区 危险因素 

分 类 号：R74[医药卫生—神经病学与精神病学]