小剂量曲安奈德玻璃体腔注射治疗视网膜静脉阻塞黄斑水肿的临床观察  

Clinical observation of intravitreal injection of small dose with triamcinolone acetonide for macular edema secondary to retinal vein occlusion

作　　者：王向华[1] 李秋明[2] 

机构地区：[1]郑州市中心医院眼科,450007 [2]郑州大学第一附属医院眼科

出　　处：《中华眼外伤职业眼病杂志》2013年第5期341-344,共4页Chinese Journal of Ocular Trauma and Occupational Eye Disease

摘　　要：目的观察小剂量曲安奈德（TA）玻璃体腔注射治疗视网膜静脉阻塞黄斑水肿的临床效果。方法对35例（35眼）视网膜静脉阻塞黄斑水肿，玻璃体腔注射TA2mg，观察视力、眼压、眼底及黄斑区视网膜厚度变化。结果注射后矫正视力均有不同程度提高，术后1周、1个月、3个月分别比术前平均提高了0．09、0．15、0．24；光相干断层扫描（OCT）检查黄斑中心凹厚度比术前平均下降了116μm、328μm、502μm；无一例眼压升高。无视网膜脱离、玻璃体积血或眼内炎发生。结论2mg曲安奈德玻璃体腔注射治疗视网膜静脉阻塞黄斑水肿是一种安全、有效的方法。Objective To observe the clinical effect of intravitreal injection with small dose of tri- amcinolone acetonide（TA） for macular edema secondary to retinal vein occlusion. Methods 35 cases （35 eyes） with macular edema secondary to retinal vein occlusion were collected, every eye was injected TA 2 mg by intravitreal injection, the visual acuity, intraocular pressure, fundus and macular retinal thickness were observed. Results The corrected vision was improved after intravitreal injection , 1 week, 1 month, 3 month respectively after treatment, the mean corrected vision increased 0.09,0.15,0. 24 compared with pre-treatment. The mean thickness of macular fovea was decreased 116 μm,328 μm,502μm by optical co- herence tomography examining. No intraocular pressure increased in all cases. No complications such as ret- inal detachment, vitreous hemorrhage or endophthalmitis occurred. Conclusion Treatment of intravitreal injection with 2mg TA for macular edema secondary to retinal vein occlusion is a safe and effective method.

关 键 词：曲安奈德 小剂量 玻璃体腔注射 视网膜静脉阻塞 黄斑水肿 

分 类 号：R774.5[医药卫生—眼科]