原发性小肠淋巴瘤临床表现、内镜特点与病理分型  

Primary small intestinal lymphoma: clinical manifestations,endoscopic features and pathological types

作　　者：杨竞[1] 温静[1] 闫斌[1] 卢忠生[1] 杨云生[1] 

机构地区：[1]中国人民解放军总医院消化科,北京100853

出　　处：《胃肠病学和肝病学杂志》2013年第5期443-445,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨原发小肠恶性淋巴瘤(PSIL)的临床表现、内镜特点和病理分型。方法回顾性分析经我院病理证实的40例PSIL患者的临床和内镜资料。结果 40例患者主要症状为腹痛、体质量下降、发热、腹块、血便和大便习惯改变。肿瘤位于十二指肠降部8例,十二指肠球部2例,空肠7例,回肠2例,回肠末端14例,多部位者7例。内镜下为弥漫浸润型11例,表浅病变型6例,溃疡型14例,隆起肿块型9例。病理类型均为非何杰金氏淋巴瘤。肿瘤起源于B淋巴细胞33例,T淋巴细胞7例。结论临床表现多不典型。回肠末端发病率最高,内镜及大体分型以溃疡型多见。组织病理学检查是确诊本病的主要手段。Objective To investigate the clinical manifestations, endoscopic features and pathological types of pri- mary small intestinal lymphoma. Methods The clinical, pathological and endoscopic data of 40 cases of primary small intestinal lymphoma in our hospital were analyzed retrospectively. Results The most common symptoms were abdominal pain, loss of weight, fever, abdominal mass, blood in stools, and change in bowel habits in 40 cases. 8 cases of lesions located in descending duodenum, 2 cases in duodenal bulb, 7 cases in jejunum, 2 cases in ileum, 14 cases in terminal ileum, and multifocal lesions were found in 7 cases. These patients were all examined by endoscopy with diffuse infiltra- tive （n=ll, 22.5%）, superficial lesions （n=6, 15.0%）, ulcerative （n=14, 35.0%） and mass-forming （n=9, 22.5% ）. Pathological types were all non-Hodgkin＇ s lymphoma. The tumor might originate from the following organ- isms： B cell （n = 33） , T cell （n = 7）. Conclusion Primary small intestinal lymphoma affecting frequently the termi- nal ileum as ulcerative growth has no specific clinical manifestation. Histopathology is main diagnostic methods.

关 键 词：恶性淋巴瘤 非何杰金氏病 小肠 

分 类 号：R735.32[医药卫生—肿瘤]