再切除术前TACE对复发性肝癌预后的影响  

Influence of preoperative transcatheter arterial chemoembolization on prognosis after repeat curative hepatectomy for recurrent hepatocellular carcinoma

作　　者：颜品高 章琎[1] 潘泽亚[1] 杨云[1] 刘辉[1] 黄罡[1] 傅思源[1] 杨远[1] 周伟平[1] 吴孟超[1] 

机构地区：[1]第二军医大学附属东方肝胆外科医院肝外三科,上海200438

出　　处：《肝胆胰外科杂志》2013年第3期182-184,共3页Journal of Hepatopancreatobiliary Surgery

基　　金：国家科技重大专项艾滋病和病毒性肝炎等重大传染病防治项目(2012ZX10002016)

摘　　要：目的分析再切除术前经肝动脉化疗栓塞(TACE)对复发性肝癌术后无瘤生存率及总体生存率的影响,探讨可切除复发性肝癌术前行TACE的意义。方法回顾性分析行再次肝癌根治术的137例复发性肝癌患者的临床病理资料,分成术前TACE组(n=42)及直接手术组(n=95),进行随访。结果除手术时间外,两组患者的其他临床病理资料的差异均无统计学意义(P>0.05)。术前TACE组与直接手术组1、2、3年无瘤生存率85.7%、57.1%、40.5%,以及82.1%、63.2%、44.2%(P>0.05);1、2、3年总体生存率分别为95.2%、78.6%、66.7%,以及91.6%、83.2%、69.5%(P>0.05)。结论可切除复发性肝癌术前TACE未能提高再切除术后的无瘤生存率及总体生存率,应首选再切除术。Objective To investigate the influence of preoperative transcatheter arterial embolization （TACE） on disease-free survival rates and overall survival rates after repeat curative hepatectomy for recur- rent hepatocellular carcinoma （HCC）. Methods One hundred and thirty-seven patients with repeat curative hepatectomy for recurrent HCC were divided into two groups： preoperative TACE group （n=42） and no preoperative treatment group （n=95）. The clinical and pathological data of the two groups regarding baseline characteristics, disease-free survival rates and overall survival rates were analyzed and compared retrospectively. Results Except for operation time for the repeat hepatectomy, the baseline characteristics of the two groups were compared （P〉0.05）. There was no significant difference between the two groups regarding disease-free survival rates and overall survival rates （P〉0.05）. Conclusion Preoperative TACE for resectable recurrent HCC should be used cautiously due to the insignificant difference of the prognosis in the two groups.

关 键 词：癌 肝细胞 再次肝切除术 术后复发 肝动脉化疗栓塞 

分 类 号：R735.7[医药卫生—肿瘤]