超高频电波刀联合保妇康栓治疗宫颈上皮内瘤变78例  

Clinical observation of Leep knife combined with Baofukang suppository in the treatment of cervical intraepithelial neoplasia

作　　者：崔潇华[1] 齐金霞[1] 黄建英[1] 王玉娜[1] 张红霞[1] 

机构地区：[1]河北省沧州中西医结合医院东院区妇产科,河北沧州061000

出　　处：《河北中医》2013年第3期410-412,共3页Hebei Journal of Traditional Chinese Medicine

摘　　要：目的观察超高频电波(Leep)刀联合保妇康栓治疗宫颈上皮内瘤变(CIN)的临床疗效。方法将148例CIN患者随机分为2组,对照组70例予Leep刀治疗,治疗组78例在对照组治疗基础上加保妇康栓阴道纳入治疗,连用3个月。2组均于2个月月经干净后观察宫颈恢复情况,3、6个月后行宫颈液基薄层细胞学检查(TCT)治疗及高危型人乳头瘤病毒(HPV-DNA)检测,TCT和HPV-DNA阴性后每6个月复查1次。随访1年,统计临床疗效。结果治疗组CIN各病情分级治愈率及总治愈率均高于对照组(P<0.05),复发率低于对照组(P<0.05)。治疗组第3、6个月及1年高危型HPV-DNA转阴率均高于对照组同期(P<0.05)。结论 Leep刀联合保妇康栓治疗CIN治愈率高,复发率低,疗效显著。Objective To discuss therapeutic effect of Leep knife combined with Baofukang suppository in the treatment of cervical intraepithelial neoplasia（CIN）.Methods 148 patients with CIN were randomly divided into two groups.70 patients in control group were treated by Leep knife.78 cases in treatment group were treated by Leep knife combined with Baofukang suppository.The course was three months in two groups.Cervical recovery was observed in 2 months after menstruation clean.The therapeutic effect was contrasted by TCT and high-risk HPV-DNA in three and six months.Results The cure rate in each grade of disease and total cure rate of treatment group was higher than that in control group（P〈0.05）.The recurrence rate in treatment group was lower than that in control group（P〈0.05）.High-risk HPV-DNA negative rate at 3,6-month and 1-year in treatment group was higher than that in control group at same time（P〈0.05）.Conclusion Leep knife combined with Baofukang suppository has high cure rate,low recurrent rate and definite effect in treating CIN.

关 键 词：微波 栓剂 宫颈上皮内瘤样病变 中西医结合疗法 

分 类 号：R737.33[医药卫生—肿瘤]