循环肿瘤细胞检测技术及其临床应用研究进展  

Research progress of circulating tumor cells detection and its clinical application

作　　者：高杰[1] 于法常[2] 崔凯[2] 张波[2] 李胜[1] 

机构地区：[1]济南大学山东省医学科学院医学与生命科学学院,济南250117 [2]山东省肿瘤防治研究院肝胆外科,济南250117

出　　处：《国际外科学杂志》2013年第5期327-331,共5页International Journal of Surgery

基　　金：973课题子课题（No.2011CB504302）

摘　　要：肿瘤细胞脱落、侵袭并进入血液循环是实现肿瘤转移的最初阶段，并为最终形成临床转移灶提供可能。深入研究循环肿瘤细胞有助于对肿瘤转移机制的了解，可为抗转移治疗提供依据。本文将对循环肿瘤细胞的检测技术及临床意义作一综述。Cancer cell exfoliation,invasion and entry into circulation system is the early event with metastasis, which provide the possibility to formation of clinical metastase. Further research about the circulating cancer cells can help us to understand the mechanism of metastasis and offer the scientific proof against anti- metastasis. The de- tection of circulating tumor cells and clinical significance were reviewed.

关 键 词：肿瘤细胞 循环 肿瘤标记 生物学 肿瘤转移 检测技术 

分 类 号：R730[医药卫生—肿瘤]