踝臂血压指数对于脑梗死并发急性冠脉事件的临床应用价值  

Correlation between ankle/brachial blood pressure index and stroke patients with acute coronary heart disease

作　　者：李翠华 刘煜敏[2] 孔朝红[2] 陈杭英 付蓓蓓[2] 谢玉[2] 

机构地区：[1]武钢总医院神经内科,武汉430070 [2]武汉大学中南医院神经内科,武汉430071

出　　处：《中国实用神经疾病杂志》2013年第10期22-25,共4页Chinese Journal of Practical Nervous Diseases

摘　　要：目的初步探讨踝臂血压指数(ABI)对于脑梗死伴发急性冠脉事件的临床应用价值。方法按照临床表现采用配对设计的原则,连续收集我院2009-08—2012-02神经内科因脑梗死住院的患者(45～85岁),分为入院后并发冠脉事件患者组(实验组,ADP组)和非冠心病组(配对对照组,NADP组),统计一般的心脑血管病危险因素和入院后不同时间段的ABI值,以及口服硝酸甘油后的ABI值,采用相关回归分析探讨ABI与患者并发冠心病的关系。结果 (1)共选取175例患者,其中ADP组43例(男25例,女18例),NADP组132例(男74例,女58例),2组患者在一般的心脑血管病危险因素比较差异无统计学意义,具有可比性(P=0.383)。(2)各组患者ABI值比较:ADP组患者与NADP对照组比较ABI值明显下降,2组间差异具有统计学意义(P=0.036);ADP组患者并发急性冠脉事件前后的ABI值差异具有统计学意义,ADP组患者并发急性冠脉事件后ABI值明显下降,差异有统计学意义(P=0.018);口服硝酸甘油后,复测患者的ABI值,发现ABI的值明显增加(P=0.004)。(3)相关分析结果显示,ABI<0.90时与患者发生急性冠脉事件的相关系数r=0.76(P<0.01),与急性冠脉事件的发生呈正相关。结论老年脑梗死患者易合并冠心病,ABI检测操作简单,可作为简易识别患者心脏血管病变提供一参考依据,可作为入院后的常规检测项目,提高识别高危因素患者。Objective To explore the correlation between ABI and acute coronary heart disease and evaluation uf VBI in judging whether a stroke patient with acute coronary heart disease. Methods Patients with cerebral infarction Neurology （45- 85 years） of our hospital from August 2009 to February 2012 were collected. Then they were divided into two groups： patients with acute coronary heart disease （experimental group, ADP group） and nomcoronary heart disease patient group （NADPgroup）. The general statistics of cardiovascular disease risk factors, ABI detection value, and ABI values of administration of nitroglycerin were collected, and meanwhile we used correlation and regression analysis to evaluate the relationship between ABI and acute coronary heart disease. Results Totally 175 patients were selected, of which 43 ADP group patients included 25 males and 18 females and 132 NADP group cases included 74 males and 58 females. There were no significant differences in the general risk factors of cardiovascular diseases between the two groups. The ABI scores were significantly decreased while with acute coronary heart disease, but ABI value increased significantly after the nitroglycerin intervention within （t= 5. 280, P〈 0.01）. Statistics analysis the correlation coefficient of ABI d0.90 and the patients with coronary heart disease was 0.76 （P〈 0.01）, which showed that there was a positive correlation between ABI〈0.90 and the incidence of coronary heart dis ease. Conclusion Elderly patients with cerebral infarction are easy to suffer from coronary heart disease. ABI can serve as a routine admission test items because ABI test is a simple and easy identification method to provide a reference to judge whether an elderly stroke patient with acute cardiovascular disease.

关 键 词：踝臂血压指数 脑梗死 冠心病 

分 类 号：R743.33[医药卫生—神经病学与精神病学]