从母血中分离胎儿细胞及产前诊断应用  

Isolation of Fetal Cells from Maternal Blood and Its Application in Prenatal Diagnosis

作　　者：廖云星[1] 李名根[1] 陶寻明[1] 

机构地区：[1]中国人民解放军第533医院,云南昆明650224

出　　处：《现代诊断与治疗》2000年第5期274-277,共4页Modern Diagnosis and Treatment

摘　　要：当前国内外正在积极研究一种非侵袭性产前诊断方法———从母体外周血分离胎儿细胞进行产前诊断。孕母外周血中存在微量胎儿细胞。采用各种先进的分离富集方法 ,可获得胎儿细胞 ,通过对这些细胞进行分析 ,即可获得产前诊断信息。该技术仍处在研究阶段 ,尚存在一些问题需要解决 ,故目前还不能广泛应用于临床 ,但它的应用前景非常光明。In recent years,considerable progress has been achieved in nonivasive prenatal diagnosis using fetal cells isolated from maternal blood.Many kinds of fetal cells have been found in maternal blood,but they are often present in very small numbers.Fetal cells can be isolated and enriched from maternal blood by many advanced methods.Fetal chromosomal abnormalities,fetal sex,fetal RHD blood type and so on can be detected on isolated fetal cells.In current,there are many unanswered problems about this technique,but the outlook for nonivasive diagnosis in the future is optimistic.

关 键 词：孕母外周血 胎儿细胞 产前诊断 

分 类 号：R714.5[医药卫生—妇产科学]