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作 者:张莲莲[1]
机构地区:[1]吉林市北华大学附属医院,吉林吉林132000
出 处:《中国民康医学》2013年第9期11-12,63,共3页Medical Journal of Chinese People’s Health
摘 要:目的:观察荆花胃康胶丸四联疗法治疗消化性溃疡(PU)的疗效和根除幽门螺旋杆菌(Hp)的效果。方法:将84例幽门螺旋杆菌(Hp)感染阳性消化性溃疡患者随机分为治疗组和对照组,每组42例。治疗组用荆花胃康胶丸+奥美拉唑+克拉霉素+阿莫西林;对照组用奥美拉唑+克拉霉素+阿莫西林,抗生素均服用7 d,其余药物服用30 d。观察治疗后两组患者的疗效和不良反应。结果:治疗组和对照组总有效率分别为92.86%和78.57%,有显著性差异(P<0.05),幽门螺旋杆菌清除率分别为92.86%和76.19%,有显著性差异(P<0.05)。结论:荆花胃康胶丸四联疗法治疗消化性溃疡临床疗效显著,无明显不良反应。Objective: To observe the efficacy of Jinghuaweikang capsule quadruple therapy for peptic ulcer (PU) and the effect of eradicating helicobacter pylori (Hp). Methods: 84 patients of peptic ulcer with helicobacter pylori (Hp) infection - positive were randomly divided into two groups, each group was composed of 42 cases. The treatment group was treated with quadruple therapy with Jinghuaweikang (capsules~ + omeprazole + clarithromycin +~moxicillin; the control group was treated with triple therapy ( ome- prazole + clarithromycin + amoxicillin) . All the antibiotics'were administered for 7 days, and the others for 30 days. The curative effect and adverse reaction of two groups were observed after the treatment. Results: The ulcer healing rates of the treatment group and the control group were 92.86% and 78.57%, which has significant difference (P 〈 0.05), the helicobacter pylori eradication rates were 92.86% and 76.19%, which has significant difference (P 〈0.05 ). Conclusions: The efficacy of Jinghuaweikang capsule quad- ruple therapy for the treatment of peptic ulcer is significant, and there is no obvious adverse reactions.
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