无症状脑梗死患者胱抑素C、同型半胱氨酸和血脂的相关性分析  

Analysis of the relationship of levels of cystatin C, homocysteine, cholesterols in patients with silent cerebral infarction

作　　者：陈荣波[1] 曾琼[1] 魏丽玲[1] 郑璇[1] 

机构地区：[1]汕头大学医学院第一附属医院神经内科,515041

出　　处：《中华脑血管病杂志（电子版）》2013年第1期21-24,共4页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

摘　　要：目的分析无症状脑梗死患者血清胱抑素C、同型半胱氨酸(Hcy)、血脂等危险因素,探讨其以上指标与无症状脑梗死的相关性。方法选取84例经头颅磁共振(MR)诊断为无症状脑梗死(SCI)患者为实验组及57例头颅MR正常患者为对照组,观察临床危险因素及相关实验室检验指标,进行统计学分析。结果无症状脑梗死血胱抑素C(CysticC)、同型半胱氨酸(Hcy)、血脂指标中低密度脂蛋白(LDL)、脂蛋白a[Lp(a)]水平均高于对照组,两组间的差异均具有统计学意义(P<0.05)。结论胱抑素C、同型半胱氨酸、血脂指标中LDL、Lp(a)的升高均是无症状脑梗死发病的的危险因素。Objective To analysis the levels of serum cystatin C , homocysteine, cholesterols in patients with silent cerebral infarction and to explore the relationships between them and silent cerebral infarction . Methods In 84 cases of silent cerebral infarction patients which were diagnosed by brain magnetic resonance imaging （ MRI ） and 57 normal control cases, the clinical risk factors and the levels of serum cystatin C , homocysteine, cholesterols were recorded and analyzed. Results The leves of cystatin C, homocysteine（Hcy）, low-density lipoprotein （ LDL ） and lipoprotein （a）[Lp （ a ） ] are higher in silent cerebral infarction （ SCI ） group than those in the control group, and there were statistical significance （P〉0.05）. Conclusion Increased levels of cystatin C ,homocysteine, LDL and Lp （ a ） have been related with silent cerebral infarction.

关 键 词：无症状脑梗死 胱抑素C 同型半胱氨酸 血脂 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]