偏头痛患者和健康人群颅内动脉血液流变学的比较研究  

A COMPARATIVE STUDY OF THE HEMORHEOLOGY OF INTRACRANIAL ARTERIES BETWEEN PATIENTS WITH MIGRAINE AND HEALTHY PEOPLE

作　　者：佘子瑜[1] 凌文通[1] 

机构地区：[1]中山市人民医院,广东中山528403

出　　处：《现代医院》2013年第5期31-33,共3页Modern Hospitals

摘　　要：目的分析偏头痛患者发作期、间歇期的颅内大动脉血流速度与正常人群是否存在差异。方法选择2009年8月～2011年8月在中山市人民医院神经内科就诊的偏头痛住院患者80名和50名健康对照,分别测量大脑中动脉(MCA)、前动脉(ACA)、后动脉(PCA)、基底动脉(BA)以及椎动脉(VA)的血流速度,分析比较偏头痛患者发作期、间歇期的颅内大动脉血流速度是否与正常人群存在统计学差异。结果偏头痛组在发作期各动脉的血流速度低于对照组;偏头痛组在间歇期大部分动脉的血流速度与对照组没有统计学差异,偏头痛患者组所有颅内动脉在发作期时的血流速度均低于间歇期。结论在偏头痛患者的间歇期、发作期测定患者颅内动脉血管的收缩、扩张状态,有利于对不同患者采取针对性的用药,消除血管的不正常状态,缓解患者的症状。Objective To analyze whether there is difference between the intracranial artery blood flow ve- locity of migraine patient in outbreak or intermit period and normal people. Methods August 2009 - August 2011 in Zhongshan City People＇s Hospital, Department of Neurology, 80 hospitalized patients with migraine and 50 healthy controls were measured the blood flow velocity of middle cerebral artery （ MCA）, anterior cerebral artery （ ACA）, post cerebral arterial （PCA） , basilar artery （BA） and vertebral artery （VA）. Analyze the outcomes of patients in outbreak or intermit period to find out whether there is statistic difference between patients and normal population. Re- suits In migraine groups at outbreak the blood flow velocity in all arteries were lower than control group; in migraine group in intermittent period the blood flow velocity of most arteries had not statistic difference comparing with normal population; in migraine group the blood flow velocity of all arteries at outbreak were lower than those in intermittent period. Conclusion To determine the contraction and expansion state of intracranial arteries of migraine patients in outbreak and intermittent period is in favor of taking target medication for different patients to eliminate the abnormal state of the blood vessels to ease the symptoms.

关 键 词：偏头痛 经颅多普勒超声 血液流变学 

分 类 号：R747.2[医药卫生—神经病学与精神病学]