不同产地鱼腥草药材挥发油成分的研究  

Study on Volatile Components of Herba Houttuyniae from Different Origins

作　　者：宋琛超[1] 易伦朝[1] 梁逸曾[1] 

机构地区：[1]中南大学化学化工学院中草药现代化研究所,湖南长沙410083

出　　处：《分析测试学报》2013年第5期559-564,共6页Journal of Instrumental Analysis

基　　金：国家自然科学基金项目(21105129);中国博士后科学基金特别资助项目(200902481)

摘　　要：从定量指纹图谱的角度,结合气相色谱-质谱(GC-MS)联用技术和直观推导式演进特征投影法(HELP)分辨解析重叠色谱峰,并对广东省博罗县、云南省大理市、湖南省长沙县3个不同产地的鱼腥草(Herba Houttuyniae)药材进行比较研究。结果表明,不同产地鱼腥草药材挥发油成分的差异主要体现在物质的相对含量上,其中(-)-4-萜品醇、α-松油醇、桧烯和β-月桂烯等物质含量的差别较大。3个不同产地(-)-4-萜品醇的相对含量分别为0.19%～0.24%、4.47%～4.93%、0.03%～0.07%,α-松油醇的相对含量分别为0.17%～0.27%、0.22%～0.24%、0.07%～0.09%,桧烯的相对含量分别为0.48%～0.64%、25.2%～26.8%、0.07%～0.11%,β-月桂烯的相对含量分别为33.66%～43.36%、10.11%～11.11%、51.23%～55.39%。该研究为规范鱼腥草药材中挥发油类成分在制药和用药的实际应用提供了一些可靠的基础。In this paper,from the angle of quantitative fingerprint,the volatile constituents of Herba Houttuyniae（HH） obtained from three different origins（Boluo County of Guangdong Province,Dali City of Yunnan Province and Changsha County of Hunan Province） were investigated comparatively by gas chromatography-mass spectrometry（GC-MS） combined with HELP method,and the overlapping chromatographic peaks were analyzed.The results showed that,the differences in the volatile chemical compositions of HH from three different origins are mainly embodied in the relative contents of most compounds,including terpinen-4-ol,α-terpineol,sabinen,β-myrcene,etc.The relative contents of terpinen-4-ol in three different origins were 0.19%-0.24%,4.47%-4.93%and 0.03%-0.07%,respectively,the relative contents of α-terpineol were 0.17%-0.27%,0.22%-0.24% and 0.07%-0.09%,respectively,the relative contents of sabinen were 0.48%-0.64%,25.2%-26.8% and 0.07%-0.11%,respectively,the relative contents of β-myrcene were 33.66%-43.36%,10.11%-11.11% and 51.23%-55.39%,respectively.This study can provide some reliable foundation for volatile components of Herba Houttuyniae in regulating the pharmaceutical products and the practical application.

关 键 词：鱼腥草药材 挥发油 指纹图谱 气相色谱-质谱 重叠色谱峰 

分 类 号：O657.63[理学—分析化学] R282[理学—化学]