正电子发射计算机体层扫描-计算机断层扫描在诊断胃肠道恶性肿瘤中的临床应用  

Clinical application of positron emission tomography-computed tomography in the diagnosis of gastrointestinal tumors

作　　者：刘路光[1] 丁连安[1] 赵延东[1] 王莉莉[1] 侯钦猛[1] 

机构地区：[1]青岛大学医学院附属医院东区普外科,266061

出　　处：《肿瘤研究与临床》2013年第5期312-315,共4页Cancer Research and Clinic

摘　　要：目的 分析18氟-脱氧葡萄糖-正电子发射型计算机体层扫描-计算机断层扫描仪（18F-FDGPET-CT）在胃肠道恶性肿瘤诊断及术后随访中的应用价值.方法 39例怀疑胃肠道恶性肿瘤的患者均行全身18F-FDG PET-CT检查,并经手术或术后病理结果及随访确诊.结果 18F-FDG PET-CT显像对胃肠道恶性肿瘤原发病灶检出的灵敏度、特异度均为100.0％,在胃癌中对于转移灶的灵敏度、特异度、准确度分别为80.0％（4/5）、90.9％（10/11）、87.5 ％（14/16）,对结直肠癌转移灶的灵敏度、特异度、准确度分别为88.9％（8/9）、92.9％（13/14）、91.3％（21/23）.PET-CT诊断胃癌局部淋巴结转移的灵敏度、特异度、准确度分别为50.0％（3/6）、90.0％（9/10）、75.0％（12/16）,诊断结直肠癌局部淋巴结转移的灵敏度、特异度、准确度分别为71.4％（5/7）、93.8％（15/16）、87.0％（20/23）.结论 18F-FDGPET-CT对胃肠道恶性肿瘤的术前诊断及分期有重要价值,优于传统检查方法.Objective To explore 18F-FDG PET-CT in the detection of malignant tumors of the gastrointestinal tract.Methods 39 patients with gastrointestinal tumors who was diagnosed with operation,pathological examination,clinical and imaging follow-up undertake the whole-body 18F-FDG PET-CT.Results The sensitivity and specificity were both 100.0 % for primary malignant tumors.Gastric metastases sensitivity,specificity and accuracy were 80.0 % （4/5）,90.9 % （10/11）,87.5 % （14/16）,and the colorectal metastases sensitivity,specificity,accuracy of diagnostic results were 88.9 % （8/9）,92.9 % （13/14）,91.3 % （21/23）.The gastric cancer lymph node metastasis sensitivity,specificity and accuracy were 50.0 % （3/6）,90.0 % （9/10）,75.0 % （12/16）,in the diagnosis of colorectal local lymph node metastasis the sensitivity,specificity and accuracy were 71.4 % （5/7）,93.8 % （15/16）,87.0 % （20/23）.Conclusion The 18F-FDG PET-CT imaging for gastrointestinal malignant tumor diagnosis and residual lesions recurrence or lesions metastases of detection is of important value and better than traditional examination methods.

关 键 词：胃肠道肿瘤 18F-FDG PET—CT 诊断 转移 

分 类 号：R735[医药卫生—肿瘤] R730[医药卫生—临床医学]