31例脑胶质瘤临床预后及其影响因素分析  

Analysis on the Influencing Factors of the Prognosis on 31 Patients with Glioma

作　　者：石磊[1] 丁鹏[1] 宋晓斌[1] 

机构地区：[1]昆明医科大学第一附属医院神经外科,云南昆明650032

出　　处：《昆明医科大学学报》2013年第4期115-117,128,共4页Journal of Kunming Medical University

摘　　要：目的分析脑胶质瘤手术患者预后及其影响因素.方法收集31例脑胶质瘤患者的临床资料,分析年龄、手术切除程度、组织分型及术后放疗等对患者1 a和3 a生存率的影响.结果 31例脑胶质瘤患者1 a和3 a生存率:低级别胶质瘤者分别为64.71%和29.41%,而高级别胶质瘤者则分别为21.43%,7.14%;手术全切除次全切除者分别为56.52%和26.09%,而部分切除者分别为12.50%、0%;手术+放疗者分别为69.23%和30.77%,而单纯手术的生存率为27.78%和11.11%;年龄≤40岁者分别为56.25%和31.25%,而年龄>40岁者分别为33.33%和6.67%.结论手术切除程度、组织分型及术后放疗、年龄等是影响患者预后的主要因素,手术全切及术后放疗能显著提高患者的生存率.Objective To analyze the prognosis of glioma after operation and its influencing factors. Method Data of 31 patients with glioma were collected in this study to analyze the different influencing factors of prognosis. Results In this study, the 1-year-survival rate and 3-year-survival rate were significantly higher in the low grade of glioma compared with the patients in the high grade of glioma （64.71% and 29.41% vs 21.43 % and 7.14 %, P 〈 0.05, respectively） , were significantly higher in the patients with complete resection or subtotal resection of glioma compared with in the patients with partial resection of glioma （56.52%0 and 26.09% vs 12.50% and 0%, P 〈 0.05, respectively） , and were significantly higher in the patients with postoperative radiation and age ≤40 compared with in the patients with operation only and age 〉 40 （69.23 % and 30.77% vs 27.78 % and 11.11% , 56.25% and 31.25% vs 33.33% and 6.67% , P 〈0.05, respectively）. Conclusion Extent of resection, histologie grade, postoperative radiation and age are significant influencing factors for prognosis of patients with glioma, in which the treatment of complete resection and postoperative radiation can prolong the survival rate of patients.

关 键 词：胶质瘤 预后 手术 放疗 脑 生存率 

分 类 号：R730.264[医药卫生—肿瘤]