MRI检查在临床诊断多发硬化中的应用  

Application of MR imaging in the clinical diagnosis of multiple sclerosis

作　　者：翟继良[1] 孙钢[1] 

机构地区：[1]山东省泰安市中心医院分院影像科,山东泰安271000

出　　处：《医学影像学杂志》2013年第5期807-809,共3页Journal of Medical Imaging

摘　　要：多发性硬化(multiple sclerosis,MS)是一种复杂的自我反应性T细胞和单核细胞介导中枢神经系统白质和脱髓鞘轴突炎症的免疫性疾病,可导致神经损伤。核磁共振成像(magnetic resonance imaging,MRI)被广泛用于多发性硬化症患者的诊断与检测。随着MRI检查技术不断发展及其应用范围逐渐扩大,MRI被广泛用于MS患者的诊断与检测,成为临床实践中连续评价的必需技术。本文综述了MRI对MS的诊断、病理机制观察、患者预后情况估计以及治疗效果判定的最新进展。MS is a complex immune disease in which self-reactive T-cells and monocytes mediate inflammation of CNS white matter and demyelination of axons, leading typically to cumulative neurologic disability. MR imaging is widely used for the diagnosis of and monitoring patients with MS. Applications and protocols for MR imaging continue to evolve, prompting a need for continual reassessments of the optimal use of this technique in clinical practice. This article provides updated recommendations on the use of MR imaging in MS, including support in diagnosis, insights into pathogenesis, an understanding of prognosis relevant to individual patients, and assistance in monitoring the effects of therapy.

关 键 词：多发性硬化 磁共振成像 血脑屏障 中枢神经系统 

分 类 号：R744.5[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]