食管静脉曲张套扎术对肝功能的影响及术后再出血的危险因素分析  

Influence of endoscopic variceal ligation on liver function and risk factors of rebleeding

作　　者：王芬[1] 步光奎[1] 沈守荣[1] 唐五良[1] 徐灿霞[1] 

机构地区：[1]中南大学湘雅三医院消化内科,长沙410013

出　　处：《中南大学学报（医学版）》2013年第5期521-525,共5页Journal of Central South University ：Medical Science

摘　　要：目的:探讨肝硬化患者实施食管静脉曲张套扎术(EVL)对肝功能的影响并分析术后再出血的危险因素。方法:回顾性分析137例行EVL的肝硬化患者临床资料,根据患者术前的肝功能Child-Pugh分级将患者分为A级、B级、C级三组,分别收集患者术前及术后1周的肝功能结果,比较肝功能的变化;再根据患者术后是否发生再出血将患者分为出血组与未出血组,分析影响术后再出血的危险因素。结果:A级、B级、C级三组患者套扎后肝功能中的ALT,AST,T-Bil,D-Bil较前无显著变化(P>0.05)。共有13例患者EVL后出血,出血率为9.49%,logistic回归分析发现病程、肝功能分级、凝血酶原时间、腹水量为影响术后再出血的危险因素。结论:EVL对肝功能无明显影响,肝硬化患者的病程、肝功能分级、凝血酶原时间、腹水量为EVL后再出血的危险因素。Objective： To investigate the influence of endoscopic variceal ligation （EVL） on liver function and analyze the risk factors of rebleeding after EVL. Methods： A total of 137 cirrhotic patients with esophageal varices who received EVL were retrospectively analyzed, and divided into group A, B, and C according to the Child-Pugh scores of liver function. We compared the liver function 1 week preoperatively and postoperatively. The patients were further divided into a rebleeding group and a non-rebleeding group after the EVL, and risk factors about rebleeding were analyzed.

关 键 词：食管静脉曲张套扎术 肝功能 术后再出血 危险因素 

分 类 号：R575.2[医药卫生—消化系统]